INT6604

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Context Info
Confidence 0.14
First Reported 1992
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 3.37
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGA3) plasma membrane (ITGA3)
Anatomy Link Frequency
osteoblast 1
extracellular matrix 1
ITGA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 78.64 Quite High
Inflammation 15 68.32 Quite High
cytokine 4 67.64 Quite High
Inflammatory marker 1 9.64 Low Low
Inflammatory mediators 1 7.52 Low Low
Pain 8 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 8 100.00 Very High Very High Very High
Pancreatic Cancer 20 99.68 Very High Very High Very High
Osteoporosis 7 97.90 Very High Very High Very High
Metastasis 2 97.32 Very High Very High Very High
Disease 13 88.20 High High
Atherosclerotic Plaque 3 85.52 High High
Calcification 98 83.36 Quite High
Adhesions 12 82.40 Quite High
Diabetes Mellitus 53 82.08 Quite High
Pancreatitis 2 78.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pancreatic carcinoma showed intense staining for VLA alpha 2 and VLA alpha 6 with a diffuse distribution on the cell surface.
VLA alpha Binding (staining) of associated with pancreatic cancer
1) Confidence 0.14 Published 1992 Journal Int. J. Cancer Section Abstract Doc Link 1330937 Disease Relevance 1.05 Pain Relevance 0.08
The redistribution of VLA alpha 2 and VLA alpha 6 may reflect a loss of spatial arrangement of tumor cells and their ability to interact randomly with extracellular matrix structures during invasion and metastasis.
VLA alpha Binding (interact) of in extracellular matrix associated with cancer and metastasis
2) Confidence 0.14 Published 1992 Journal Int. J. Cancer Section Abstract Doc Link 1330937 Disease Relevance 1.24 Pain Relevance 0.07
Bone siloprotein synthesized by the osteoblast-like VSMC has recently been shown to be an angiogenic protein capable of inducing neovascularization by interacting with the alpha v beta 3 integrin [18].
alpha v beta 3 integrin Binding (interacting) of in osteoblast associated with osteoporosis
3) Confidence 0.01 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1079905 Disease Relevance 1.07 Pain Relevance 0.07

General Comments

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