INT66164

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Context Info
Confidence 0.41
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.08

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methyltransferase activity (Pnmt) cytoplasm (Pnmt)
Pnmt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 3 78.32 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Agents used as controls were SKF29661, which is a selective peripheral PNMT inhibitor, SKF64139, a PNMT inhibitor that inhibits equally both alpha-2-adrenoceptor activity and PNMT, and yohimbine, an alpha-2-adrenoceptor inhibitor that does not inhibit PNMT.
Negative_regulation (inhibitor) of PNMT Binding (yohimbine) of
1) Confidence 0.41 Published 1996 Journal Neuropsychobiology Section Abstract Doc Link 8904737 Disease Relevance 0 Pain Relevance 0.08

General Comments

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