INT66428

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Context Info
Confidence 0.05
First Reported 1995
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) nucleolus (Fos) nucleus (Fos)
DNA binding (Fos) transcription factor binding (Fos) response to stress (Fos)
Anatomy Link Frequency
spinal cord 2
Dcc (Rattus norvegicus)
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 17 99.20 Very High Very High Very High
nud 1 98.68 Very High Very High Very High
Analgesic 2 94.24 High High
Morphine 4 93.36 High High
tramadol 6 92.32 High High
primary afferent fibers 1 82.64 Quite High
parabrachial 1 75.52 Quite High
Inflammation 7 75.00 Quite High
narcan 2 47.52 Quite Low
projection neuron 1 27.84 Quite Low
Disease Link Frequency Relevance Heat
Dyspepsia 1 98.68 Very High Very High Very High
Nociception 2 94.52 High High
INFLAMMATION 7 75.00 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously reported that repetitive, noxious colorectal distention (CRD) induces c-Fos in the lumbosacral spinal cord.
colorectal distention Positive_regulation (induces) of c-Fos in spinal cord associated with spinal cord
1) Confidence 0.05 Published 1995 Journal Brain Res. Section Abstract Doc Link 8925281 Disease Relevance 0 Pain Relevance 0.82
In the rat, repetitive noxious colorectal distention (CRD) induces >200 Fos labeled cells per section in the lumbosacral segments, but few in the thoracolumbar segments, further suggesting that transient colonic nociceptive input is transduced primarily in the lumbosacral spinal cord.
colorectal distention Positive_regulation (induces) of Fos in spinal cord associated with nociception and spinal cord
2) Confidence 0.01 Published 2002 Journal Pain Section Abstract Doc Link 11790471 Disease Relevance 0.39 Pain Relevance 0.48

General Comments

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