INT66570

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Context Info
Confidence 0.78
First Reported 1996
Last Reported 2004
Negated 0
Speculated 1
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 0.37
Pain Relevance 3.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Glul) mitochondrion (Glul) lyase activity (Glul)
Golgi apparatus (Glul) intracellular (Glul) protein complex (Glul)
Anatomy Link Frequency
spinal cords 2
Glul (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 18 100.00 Very High Very High Very High
Glutamate 13 100.00 Very High Very High Very High
Neuropeptide 15 99.80 Very High Very High Very High
Spinal cord 3 99.74 Very High Very High Very High
gABA 3 98.92 Very High Very High Very High
Calcitonin gene-related peptide 3 97.24 Very High Very High Very High
qutenza 6 97.12 Very High Very High Very High
Dynorphin 9 95.92 Very High Very High Very High
Enkephalin 6 95.48 Very High Very High Very High
substance P 9 93.48 High High
Disease Link Frequency Relevance Heat
Aids-related Complex 4 99.68 Very High Very High Very High
Epilepsy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Co-localization of GFAP and GS was observed in the ARC-ME complex.
Localization (localization) of GS associated with aids-related complex
1) Confidence 0.78 Published 2004 Journal Neuroreport Section Abstract Doc Link 15076747 Disease Relevance 0.37 Pain Relevance 0.47
Patterns of co-localization of serotonin with glutamate decarboxylase (the synthetic enzyme for GABA) or each one of eight neuropeptides (calcitonin gene-related peptide, dynorphin, enkephalin, galanin, neuropeptide Y, neurotensin, substance P and somatostatin) were investigated with dual-colour confocal laser scanning microscopy in the lumbar spinal cords of three adult rats.
Spec (investigated) Localization (co-localization) of glutamate decarboxylase in spinal cords associated with somatostatin, enkephalin, calcitonin gene-related peptide, glutamate, gaba, dynorphin, neuropeptide, serotonin and substance p
2) Confidence 0.64 Published 1996 Journal Neuroscience Section Abstract Doc Link 8931011 Disease Relevance 0 Pain Relevance 0.70
A confocal microscopic survey of serotoninergic axons in the lumbar spinal cord of the rat: co-localization with glutamate decarboxylase and neuropeptides.
Localization (co-localization) of glutamate decarboxylase in spinal cord associated with glutamate, neuropeptide and spinal cord
3) Confidence 0.60 Published 1996 Journal Neuroscience Section Title Doc Link 8931011 Disease Relevance 0 Pain Relevance 1.16
Co-localization of serotonin and glutamate decarboxylase was found only in a few axons of laminae I-II but was not detected in other laminae.
Localization (Co-localization) of glutamate decarboxylase associated with glutamate and serotonin
4) Confidence 0.52 Published 1996 Journal Neuroscience Section Abstract Doc Link 8931011 Disease Relevance 0 Pain Relevance 1.12
METHODS: The study was performed by examining cell viability (MTT assay), cell toxicity [lactate dehydrogenase (LDH) release in the medium], glutamine synthetase (GS) activity, reactive oxygen species (ROS) production, lipoperoxidation level (malondialdehyde; MDA), and DNA fragmentation (COMET assay).
Localization (release) of glutamine synthetase
5) Confidence 0.36 Published 2003 Journal Epilepsia Section Body Doc Link 14511393 Disease Relevance 0 Pain Relevance 0

General Comments

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