INT66683

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Context Info
Confidence 0.73
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.49
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (B3GAT1) carbohydrate metabolic process (B3GAT1)
B3GAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 56 99.18 Very High Very High Very High
Neuropeptide 2 93.48 High High
gABA 1 90.88 High High
Inflammation 1 77.36 Quite High
Serotonin 2 75.00 Quite High
Pain 2 73.84 Quite High
Neurotransmitter 2 68.24 Quite High
tetrodotoxin 1 62.00 Quite High
antagonist 5 60.32 Quite High
alcohol 1 51.16 Quite High
Disease Link Frequency Relevance Heat
Neurogenic Inflammation 1 77.36 Quite High
Nociception 1 74.88 Quite High
Pain 2 73.84 Quite High
Disease 2 73.20 Quite High
Increased Venous Pressure Under Development 2 72.52 Quite High
Adhesions 3 60.96 Quite High
Cancer 2 59.52 Quite High
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NK1 receptors were localised with antibodies against the C-terminus of this receptor.
Localization (localised) of NK1
1) Confidence 0.73 Published 1996 Journal Histochem. Cell Biol. Section Abstract Doc Link 8985744 Disease Relevance 0 Pain Relevance 0.36
1 integrin (Anti-Integrin alpha6, clone NKI-GoH3 from Chemicon; ; or Affinity purified anti-mouse integrin ?
Localization (clone) of NKI
2) Confidence 0.73 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570688 Disease Relevance 0.12 Pain Relevance 0.03
SP, in turn, stimulates hippocampal [3H]-ACh release through NK1 receptors present on cholinergic terminals.
Localization (release) of NK1
3) Confidence 0.68 Published 1996 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 8938661 Disease Relevance 0.07 Pain Relevance 0.24
Substance P, hemokinin 1 and endokinin A and B show preference for NK1 (13–15), neurokinin A for NK2 and neurokinin B for NK3.
Localization (preference) of NK1 associated with substance p
4) Confidence 0.34 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC552970 Disease Relevance 0.30 Pain Relevance 0.49

General Comments

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