INT66726

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Context Info
Confidence 0.45
First Reported 1996
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.41
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Rars) nucleolus (Rars) nucleus (Rars)
ligase activity (Rars) cytoplasm (Rars)
Rars (Rattus norvegicus)
Pain Link Frequency Relevance Heat
c fibre 5 99.80 Very High Very High Very High
substance P 1 91.84 High High
Inflammation 1 89.84 High High
Disease Link Frequency Relevance Heat
Infection 1 100.00 Very High Very High Very High
Cough 14 99.98 Very High Very High Very High
Hypersensitivity 2 93.44 High High
Neurogenic Inflammation 1 89.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several major issues have been discussed in these presentations, including the pharmacologic, physiologic and neurochemical characteristics of the cough receptors; the effect of phenotypic switch of the rapidly adapting receptors (RARs) during chronic airway infection; the interaction between RARs and C-fiber afferents both at the receptor level and in the centrally mediated reflex pathway; and the cellular mechanisms and ion channel species involved in the hypersensitivity of the cough receptors.
Regulation (effect) of RARs Binding (interaction) of associated with c fibre, hypersensitivity, cough and infection
1) Confidence 0.45 Published 2002 Journal Pulm Pharmacol Ther Section Abstract Doc Link 12099767 Disease Relevance 0.79 Pain Relevance 0.10
The strength and pattern of cough depends on the sites of the airway that are stimulated and the local and central reflex interactions of the RARs and C fiber receptors.
Regulation (depends) of RARs Binding (interactions) of associated with c fibre and cough
2) Confidence 0.33 Published 1996 Journal J. Allergy Clin. Immunol. Section Abstract Doc Link 8939181 Disease Relevance 0.62 Pain Relevance 0.45

General Comments

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