INT66882

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Context Info
Confidence 0.73
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.64
Pain Relevance 1.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sort1) endosome (Sort1) transport (Sort1)
Golgi apparatus (Sort1) endoplasmic reticulum (Sort1) intracellular (Sort1)
Anatomy Link Frequency
spinal cord 1
nerve 1
interneurons 1
Sort1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
GABAergic 5 99.84 Very High Very High Very High
Nerve growth factor 2 99.18 Very High Very High Very High
dorsal root ganglion 1 98.88 Very High Very High Very High
Sciatic nerve 3 98.44 Very High Very High Very High
tetrodotoxin 1 96.88 Very High Very High Very High
Action potential 2 96.40 Very High Very High Very High
Pain 7 96.24 Very High Very High Very High
Dorsal horn 2 95.92 Very High Very High Very High
Spinal cord 1 95.16 Very High Very High Very High
agonist 5 95.00 High High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 98.40 Very High Very High Very High
Pain 5 96.24 Very High Very High Very High
Low Back Pain 1 89.40 High High
Nociception 1 75.00 Quite High
Nervous System Injury 1 75.00 Quite High
Injury 1 67.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Triple immunofluorescent staining of recorded interneurons demonstrated the expression of NTS1 on GABAergic interneurons.
Gene_expression (expression) of NTS1 in interneurons associated with gabaergic
1) Confidence 0.73 Published 2008 Journal J. Neurophysiol. Section Abstract Doc Link 18337367 Disease Relevance 0 Pain Relevance 0.61
COS 8 augmented the increase of nerve growth factor, brain-derived neurotrophic factor, and NT-3 mRNA expression in the distal stump of the axotomized sciatic nerve.
Gene_expression (expression) of NT-3 in nerve associated with nerve growth factor and sciatic nerve
2) Confidence 0.65 Published 1996 Journal J. Neurosci. Res. Section Abstract Doc Link 8951669 Disease Relevance 0.14 Pain Relevance 0.40
We first established, using immunoblotting and immunohistochemical approaches, that NTS1 receptors were present in small- and medium-sized dorsal root ganglion cells and localized in the superficial layers of the dorsal horn of the spinal cord.
Gene_expression (present) of NTS1 in spinal cord associated with ganglion cysts, dorsal root ganglion, dorsal horn and spinal cord
3) Confidence 0.39 Published 2008 Journal J. Neurochem. Section Abstract Doc Link 18182046 Disease Relevance 0.50 Pain Relevance 0.96

General Comments

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