INT66958

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Context Info
Confidence 0.65
First Reported 1996
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.40
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Pura) cell proliferation (Pura) nucleus (Pura)
DNA binding (Pura) transcription factor binding (Pura) cytoplasm (Pura)
Anatomy Link Frequency
brain 1
lung epithelium 1
lungs 1
Pura (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 14 99.76 Very High Very High Very High
addiction 4 93.08 High High
Morphine 3 92.64 High High
opiate 2 78.32 Quite High
tolerance 2 77.76 Quite High
Somatostatin 1 73.00 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 10 99.76 Very High Very High Very High
Hypersensitivity 6 98.96 Very High Very High Very High
Morphine Dependence 2 93.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To investigate the function of ssCRE-BP in the brain, recombinant glutathione-S-transferase (GST) fusion proteins containing ssCRE-BP were expressed in bacterial systems.
Gene_expression (expressed) of ssCRE-BP in brain
1) Confidence 0.65 Published 1996 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 8959022 Disease Relevance 0 Pain Relevance 0.40
Immunohistochemistry showed that ssCRE-BP/Pur alpha is primarily distributed in the lung epithelium.
Gene_expression (distributed) of ssCRE-BP in lung epithelium
2) Confidence 0.65 Published 1998 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 9920198 Disease Relevance 0.69 Pain Relevance 0.31
The expression and DNA-binding activity of 45-kDa ssCRE-BP/Pur alpha were significantly increased in the sensitized rat lungs 24 hr after antigen challenge, but not in those of rats nonsensitized or sensitized with ovalbumin and challenged with saline.
Gene_expression (expression) of ssCRE-BP in lungs
3) Confidence 0.29 Published 1998 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 9920198 Disease Relevance 0.71 Pain Relevance 0.33

General Comments

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