INT66978

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Context Info
Confidence 0.48
First Reported 1996
Last Reported 2004
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 7
Disease Relevance 6.13
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pon1) extracellular region (Pon1)
Anatomy Link Frequency
heart 3
Pon1 (Mus musculus)
Pon1 - Q192R (4)
Pain Link Frequency Relevance Heat
Angina 55 94.80 High High
Disease Link Frequency Relevance Heat
Coronary Artery Disease 439 99.96 Very High Very High Very High
Coronary Stenosis 1 95.92 Very High Very High Very High
Renal Disease 18 95.76 Very High Very High Very High
Hyperlipidemia 24 95.08 Very High Very High Very High
Cv General 3 Under Development 43 94.80 High High
Myocardial Infarction 19 94.28 High High
Diabetes Mellitus 45 93.80 High High
Disease 66 86.80 High High
Disorder Of Lipid Metabolism 43 84.88 Quite High
Obesity 12 83.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The file is named 'summaryT' and the title of the table is 'Summary of studies examining the association between PON1 Q192R polymorphism and coronary heart disease'.
PON1 (Q192R) Spec (examining) Binding (association) of in heart associated with coronary artery disease
1) Confidence 0.48 Published 2004 Journal BMC Genet Section Body Doc Link PMC449704 Disease Relevance 0.63 Pain Relevance 0.06
The association of PON1 Q192R polymorphism with coronary heart disease in the British Women's Heart and Health Study
PON1 (Q192R) Binding (association) of in Heart associated with coronary artery disease
2) Confidence 0.37 Published 2004 Journal BMC Genet Section Body Doc Link PMC449704 Disease Relevance 1.00 Pain Relevance 0
Can the principles of Mendelian randomisation be used to deduce the effects of PON1 activity on CHD from the PON1 genotype-CHD association results?
PON1 Binding (genotype) of associated with coronary artery disease
3) Confidence 0.37 Published 2004 Journal BMC Genet Section Body Doc Link PMC449704 Disease Relevance 0.91 Pain Relevance 0
Can the principles of Mendelian randomisation be used to deduce the effects of PON1 activity on CHD from the PON1 genotype-CHD association results?
PON1 Binding (activity) of associated with coronary artery disease
4) Confidence 0.37 Published 2004 Journal BMC Genet Section Body Doc Link PMC449704 Disease Relevance 0.91 Pain Relevance 0
We identified 38 studies that assessed the association between PON1 Q192R genotype and CHD [14-51].
PON1 (Q192R) Binding (association) of associated with coronary artery disease
5) Confidence 0.37 Published 2004 Journal BMC Genet Section Body Doc Link PMC449704 Disease Relevance 0.69 Pain Relevance 0.05
There was no evidence from any of these that PON1 Q192R genotype was associated with CHD.
PON1 (Q192R) Binding (genotype) of associated with coronary artery disease
6) Confidence 0.36 Published 2004 Journal BMC Genet Section Body Doc Link PMC449704 Disease Relevance 1.06 Pain Relevance 0.09
We investigated the association of paraoxonase (PON) gene polymorphism with both the occurrence of coronary heart disease (CHD) and the severity of coronary artery stenosis in Japanese subjects.
paraoxonase Binding (association) of in heart associated with coronary stenosis and coronary artery disease
7) Confidence 0.02 Published 1996 Journal Int. J. Cardiol. Section Abstract Doc Link 8960946 Disease Relevance 0.79 Pain Relevance 0.06

General Comments

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