INT67033

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Context Info
Confidence 0.54
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 14
Total Number 14
Disease Relevance 10.35
Pain Relevance 2.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crp) extracellular region (Crp)
Anatomy Link Frequency
lymph nodes 1
coronary artery 1
plasma 1
leukocytes 1
neutrophil 1
Crp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 15 99.60 Very High Very High Very High
Inflammation 62 99.00 Very High Very High Very High
cva 32 95.40 Very High Very High Very High
ischemia 1 94.40 High High
Central nervous system 10 93.96 High High
Prostatitis 2 89.28 High High
palliative 2 87.76 High High
Angina 11 75.00 Quite High
spinal inflammation 2 75.00 Quite High
aspirin 3 74.24 Quite High
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 27 100.00 Very High Very High Very High
Cancer 62 99.98 Very High Very High Very High
INFLAMMATION 105 99.00 Very High Very High Very High
Jaundice 1 98.56 Very High Very High Very High
Nicotine Addiction 118 97.78 Very High Very High Very High
Weight Loss 1 97.64 Very High Very High Very High
Disease 90 97.44 Very High Very High Very High
Metastasis 4 96.60 Very High Very High Very High
Central Nervous System Vasculitis 3 95.88 Very High Very High Very High
Cv General 3 Under Development 42 95.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, a proinflammatory cytokine that also promotes C-reactive protein release (24).
Localization (release) of C-reactive protein associated with cytokine
1) Confidence 0.54 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779284 Disease Relevance 1.40 Pain Relevance 0.12
To further explain the relationship between smoking exposure and C-reactive protein, to increase the power to detect a trend, and to reduce residual confounding, C-reactive protein was categorized into three levels: under 2.1 mg/l (undetectable), 2.1–9.9 mg/l (mildly elevated), and ?
Localization (categorized) of C-reactive protein associated with nicotine addiction
2) Confidence 0.42 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1160573 Disease Relevance 1.28 Pain Relevance 0.18
By comparing the urethroadnexitis group and the non-infected group with regard to other clinical parameters, we found a significantly increased C-reactive protein in the infected group.
Localization (found) of C-reactive protein
3) Confidence 0.38 Published 1996 Journal Z Rheumatol Section Abstract Doc Link 8967185 Disease Relevance 1.07 Pain Relevance 0.28
In 10 patients of each group, haematocrit, white cell count, C-reactive protein, glucose, cortisol, adrenocorticotrophic hormone, beta-endorphin immunoreactivity, interleukin-6 and urine excretion of epinephrine and norepinephrine were measured preoperatively and during the first 44 postoperative hours.
Localization (excretion) of C-reactive protein in urine
4) Confidence 0.25 Published 2001 Journal Eur J Anaesthesiol Section Body Doc Link 11473560 Disease Relevance 0.08 Pain Relevance 0
Both LMWHs reduced the release of vWF in plasma (as well as C-reactive protein) compared with UFH.
Localization (release) of C-reactive protein in plasma
5) Confidence 0.08 Published 2003 Journal Am. J. Cardiol. Section Abstract Doc Link 12686329 Disease Relevance 0.92 Pain Relevance 0.54
CONCLUSIONS: In patients with unstable angina, stenting is associated by immediate neutrophil activation followed by release of inflammatory cytokines (IL-6, IL-8, IL-11) and C-reactive protein elevation.
Localization (release) of C-reactive protein in neutrophil
6) Confidence 0.08 Published 2005 Journal Coron. Artery Dis. Section Body Doc Link 15654202 Disease Relevance 0 Pain Relevance 0
CONCLUSIONS: Direct coronary artery stenting is associated with an early polymorphonuclear neutrophils activation followed by release of inflammatory cytokines (interleukin-6, interleukin-8, interleukin-12) and C-reactive protein elevation in both stable and unstable patients.
Localization (release) of C-reactive protein in coronary artery
7) Confidence 0.07 Published 2006 Journal Int. J. Cardiol. Section Body Doc Link 16316691 Disease Relevance 0.18 Pain Relevance 0
Multivariate analysis indicated that ten factors had a significant independent effect on survival: chemotherapy, surgery, tumor localization, elevated C-reactive protein, elevated CeA, CA 19-9 (>30 x nl), jaundice at diagnosis, weight loss >10%, distant metastases, and Karnofsky performance status.
Localization (localization) of C-reactive protein associated with weight loss, cancer, jaundice and metastasis
8) Confidence 0.07 Published 2009 Journal J Chemother Section Abstract Doc Link 20071292 Disease Relevance 0.93 Pain Relevance 0.17
In our patient, steroids resulted in a partial improvement of the clinical status and normalization of the CSF and C-reactive protein indicating that the clinical deterioration of the late phase of the evolution was probably due to the cerebral angiitis.
Localization (normalization) of C-reactive protein associated with central nervous system vasculitis
9) Confidence 0.06 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2663463 Disease Relevance 1.35 Pain Relevance 0.21
Using a training set of 91 stage I data sets, representing 61 individual samples, and an equivalent number of controls, an 11-analyte profile, composed of CA-125, CA 19-9, EGF-R, C-reactive protein, myoglobin, apolipoprotein A1, apolipoprotein CIII, MIP-1?
Localization (apolipoprotein A1) of C-reactive protein associated with disorder of lipid metabolism
10) Confidence 0.05 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2643010 Disease Relevance 0.83 Pain Relevance 0
Using a training set of 91 stage I data sets, representing 61 individual samples, and an equivalent number of controls, an 11-analyte profile, composed of CA-125, CA 19-9, EGF-R, C-reactive protein, myoglobin, apolipoprotein A1, apolipoprotein CIII, MIP-1?
Localization (composed) of C-reactive protein associated with disorder of lipid metabolism
11) Confidence 0.05 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2643010 Disease Relevance 0.78 Pain Relevance 0
There was no statistical difference between patients who presented high white blood count and C reactive protein, and those with low counts concerning the characteristic of lymph nodes.
Localization (presented) of reactive protein in lymph nodes
12) Confidence 0.04 Published 2010 Journal Korean Journal of Pediatrics Section Body Doc Link PMC3004496 Disease Relevance 0.29 Pain Relevance 0
IL-6 stimulates secretion of C-reactive protein, an important biomarker for pro-inflammatory status in several diseases, and polymorphisms in the promoter region have been associated with C-reactive protein circulating levels.
Localization (secretion) of C-reactive protein associated with inflammation and disease
13) Confidence 0.02 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC3006374 Disease Relevance 0.94 Pain Relevance 0.48
In addition, mortality, length of ICU stay, positive blood cultures and positive tracheobronchial secretions, as well as changes in maximal leukocytes, C-reactive protein (CRP) and interleukin-6 (IL-6), were recorded.
Localization (secretions) of C-reactive protein in leukocytes
14) Confidence 0.01 Published 2008 Journal Crit Care Section Body Doc Link PMC2575586 Disease Relevance 0.31 Pain Relevance 0.05

General Comments

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