INT67078

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Context Info
Confidence 0.48
First Reported 1996
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 4.84
Pain Relevance 2.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ifng) extracellular region (Ifng)
Ifng (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 11 100.00 Very High Very High Very High
Morphine 15 99.92 Very High Very High Very High
Enkephalin 8 99.52 Very High Very High Very High
palliative 1 96.04 Very High Very High Very High
narcan 2 95.56 Very High Very High Very High
cytokine 5 93.92 High High
opioid receptor 5 93.36 High High
Opioid 1 91.20 High High
Neuropeptide 1 86.64 High High
Opioid receptor 1 1 77.72 Quite High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 225 100.00 Very High Very High Very High
Impaired Glucose Tolerance 13 100.00 Very High Very High Very High
Cancer 5 99.92 Very High Very High Very High
Necrosis 1 99.64 Very High Very High Very High
Amputation 1 99.56 Very High Very High Very High
Cardiovascular Disease 15 98.44 Very High Very High Very High
Hyperglycemia 3 97.12 Very High Very High Very High
Metastasis 2 95.56 Very High Very High Very High
Skin Cancer 2 92.92 High High
Targeted Disruption 2 92.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The stimulative effect of the low (2.5 mg/kg bw) dose, that was observed only if MENK was injected p.m., was associated with the IL production and IFN gamma as demonstrated by abolishing the effect by specific antibodies.
IFN gamma Binding (associated) of associated with enkephalin
1) Confidence 0.48 Published 1998 Journal Neuropeptides Section Abstract Doc Link 9571645 Disease Relevance 0 Pain Relevance 0.77
However, only when NFATc1 was co-overexpressed with c-fos was the inhibitory effect of morphine on IFN-gamma promoter counteracted.
IFN-gamma Binding (counteracted) of associated with morphine
2) Confidence 0.33 Published 2003 Journal J. Biol. Chem. Section Abstract Doc Link 12842891 Disease Relevance 0.22 Pain Relevance 1.21
Results show that addition of IFN gamma alone results in a slight suppression of FLV expression, whereas treatment with both AZT and IFN gamma inhibits FLV replication significantly.
IFN gamma Binding (treatment) of
3) Confidence 0.16 Published 1996 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 8968350 Disease Relevance 0.06 Pain Relevance 0.25
Firstly, perfusion with gamma-interferon, tumour necrosis factor- alpha and melphalan was carried out, after which the tumour had been reduced to one third of its initial volume.
gamma-interferon Binding (perfusion) of associated with necrosis and cancer
4) Confidence 0.08 Published 2000 Journal Eur J Surg Oncol Section Abstract Doc Link 10744942 Disease Relevance 0.91 Pain Relevance 0.10
Polymorphisms were tested for association with glucose tolerance (normal vs IFG and T2DM combined) by calculating a chi(2) statistic and corresponding P values, whereas associations with quantitative measures of glucose tolerance, IS and insulin secretion were tested using mixed linear models implemented in the MIXED procedure of sas (SAS Institute, Cary, NC, USA).
IFG Binding (association) of associated with diabetes mellitus, tolerance and impaired glucose tolerance
5) Confidence 0.06 Published 2008 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 18518884 Disease Relevance 0.86 Pain Relevance 0.37
Although some studies have found that the 1997 IFG definition is associated with significantly increased risk for CVD,[2324] others have shown no significantly increased risk for CVD with the 1997 IFG definition.[25–27]
IFG Binding (associated) of associated with cardiovascular disease
6) Confidence 0.04 Published 2010 Journal Journal of Cardiovascular Disease Research Section Body Doc Link PMC2982198 Disease Relevance 1.20 Pain Relevance 0.03
These variants, as well as those in chromosome 11 (rs7480010 and rs9300039, r2 = 0.037), were not associated with type 2 diabetes or IFG.
IFG Binding (associated) of associated with diabetes mellitus
7) Confidence 0.01 Published 2008 Journal Diabetes Section Body Doc Link PMC2551696 Disease Relevance 0.99 Pain Relevance 0
We first examined the association with the risk of type 2 diabetes and IFG (Table 2).
IFG Spec (examined) Binding (association) of associated with diabetes mellitus
8) Confidence 0.01 Published 2008 Journal Diabetes Section Body Doc Link PMC2551696 Disease Relevance 0.60 Pain Relevance 0

General Comments

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