INT67112

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Context Info
Confidence 0.58
First Reported 1996
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 27
Total Number 30
Disease Relevance 21.17
Pain Relevance 7.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
monocyte 2
macrophages 1
CD86 1
synovial fluid 1
blood 1
fc (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 597 99.84 Very High Very High Very High
fluoxetine 8 99.70 Very High Very High Very High
Inflammatory response 56 99.24 Very High Very High Very High
tolerance 13 99.20 Very High Very High Very High
Inflammation 327 99.12 Very High Very High Very High
agonist 2 98.88 Very High Very High Very High
Arthritis 409 98.72 Very High Very High Very High
antagonist 5 98.64 Very High Very High Very High
Adalimumab 121 98.04 Very High Very High Very High
imagery 8 97.90 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 12 100.00 Very High Very High Very High
Coronary Artery Disease 4 99.98 Very High Very High Very High
Stress 74 99.96 Very High Very High Very High
Rheumatoid Arthritis 598 99.84 Very High Very High Very High
Infection 148 99.80 Very High Very High Very High
Arthus Reaction 72 99.62 Very High Very High Very High
Diabetes Mellitus 21 99.24 Very High Very High Very High
INFLAMMATION 387 99.12 Very High Very High Very High
Arthritis 426 98.72 Very High Very High Very High
Disease 344 97.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, imaging of MTFF is carried out by fluorescence cardioscopy (FC).Sixty-six patients with coronary artery disease underwent FC using fluorescein as an indicator of MTFF because this dye exhibits fluorescence in tissue fluid but not in the blood.
Neg (not) Positive_regulation (underwent) of FC in blood associated with coronary artery disease and imagery
1) Confidence 0.58 Published 2010 Journal Int Heart J Section Abstract Doc Link 20558903 Disease Relevance 0.17 Pain Relevance 0.10
However, in animals co-administered with [WAY 100635 + fluoxetine], the maximal increase in 5-HT levels in the FC was to 215% of the respective basal value (100%), while no significant change in 5-HT was observed in dialysates from the vHi.
Positive_regulation (increase) of FC associated with urological neuroanatomy and fluoxetine
2) Confidence 0.39 Published 1996 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 8971740 Disease Relevance 0.41 Pain Relevance 0.86
Rs act in concert in many inflammatory responses, with complement both attracting and activating Fc?
Positive_regulation (activating) of Fc associated with inflammatory response
3) Confidence 0.20 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.28 Pain Relevance 0.48
Convergence of complement and Fc receptor activation in RA pathogenesis
Positive_regulation (activation) of Fc associated with rheumatoid arthritis
4) Confidence 0.20 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.17 Pain Relevance 0.43
Recent experimental data using the K/B × N arthritis model showed that the pathogenic action of anti-GPI antibodies depends on Fc?
Positive_regulation (depends) of Fc associated with arthritis
5) Confidence 0.15 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.57 Pain Relevance 0.54
RIII-deficient DBA/1 mice were almost completely protected from arthritogenic IgG1, IgG2a or IgG2b antibodies, indicating that activating Fc?
Positive_regulation (activating) of Fc
6) Confidence 0.15 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.51 Pain Relevance 0.53
A dominant role for Fc?
Positive_regulation (role) of Fc
7) Confidence 0.15 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.38 Pain Relevance 0.34
Cortical perfusion with risperidone or the alpha2A/D, 5-HT1B and 5-HT1B/1D receptor antagonists idazoxan, isamoltane or GR 127,935, respectively, dose-dependently increased 5-HT efflux in the FC.
Positive_regulation (increased) of FC associated with antagonist and urological neuroanatomy
8) Confidence 0.15 Published 1999 Journal Neuropharmacology Section Abstract Doc Link 10462130 Disease Relevance 0.46 Pain Relevance 0.43
It has been widely accepted that ICs initiate inflammatory responses in IC diseases such as arthritis or the Arthus reaction either by activation of the complement system or by the direct engagement and activation of Fc?
Positive_regulation (activation) of Fc associated with inflammatory response, disease, arthus reaction and arthritis
9) Confidence 0.14 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.21 Pain Relevance 0.45
Mice lacking the stimulatory Fc?
Positive_regulation (stimulatory) of Fc
10) Confidence 0.13 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.17 Pain Relevance 0.23
In the Arthus reaction mice model, the crucial role of the Fc?
Positive_regulation (role) of Fc associated with arthus reaction
11) Confidence 0.13 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.16 Pain Relevance 0.23
Rs in the inflammatory response, especially in Arthus reaction mice models, have resulted in a better understanding of the role of the complement system and Fc?
Positive_regulation (resulted) of Fc associated with inflammatory response and arthus reaction
12) Confidence 0.13 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.55 Pain Relevance 0.42
In regard to RA, exposure of DCs to synovial fluid from RA patients has been shown to lead to an upregulation of Fc?
Positive_regulation (upregulation) of Fc in synovial fluid associated with rheumatoid arthritis
13) Confidence 0.10 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888223 Disease Relevance 0.35 Pain Relevance 0.26
There is evidence of a normal upregulation of Fc?
Positive_regulation (upregulation) of Fc
14) Confidence 0.10 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888223 Disease Relevance 0.73 Pain Relevance 0.32
Previous research suggested that Fc?
Positive_regulation (suggested) of Fc
15) Confidence 0.08 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2529314 Disease Relevance 1.04 Pain Relevance 0.13
It has been postulated that Fc?
Positive_regulation (postulated) of Fc
16) Confidence 0.07 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888223 Disease Relevance 1.13 Pain Relevance 0.25
RIIa without changing Fc?
Neg (without) Positive_regulation (changing) of Fc
17) Confidence 0.06 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888223 Disease Relevance 0.27 Pain Relevance 0.22
RIIb expression on DCs, while increasing Fc?
Positive_regulation (increasing) of Fc
18) Confidence 0.06 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888223 Disease Relevance 0.27 Pain Relevance 0.22
As for CD86, the evaluation of Fc?
Positive_regulation (evaluation) of Fc in CD86
19) Confidence 0.06 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888223 Disease Relevance 0.75 Pain Relevance 0.29
Fc receptor activation, in addition, activates scavenger cells, promoting attack and phagocytosis.
Positive_regulation (activation) of Fc
20) Confidence 0.05 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1199616 Disease Relevance 0.34 Pain Relevance 0.12

General Comments

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