INT67134

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Context Info
Confidence 0.34
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.37
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Gusb) endoplasmic reticulum (Gusb) carbohydrate metabolic process (Gusb)
lysosome (Gusb)
Anatomy Link Frequency
central nervous system 2
Gusb (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 1 98.08 Very High Very High Very High
anesthesia 1 25.00 Low Low
Inflammatory response 1 25.00 Low Low
fibrosis 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Enkephalin 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 96.32 Very High Very High Very High
Tachycardia 28 95.20 Very High Very High Very High
Arrhythmias 2 Under Development 13 94.40 High High
Mucopolysaccharidoses 1 93.72 High High
Mucopolysaccharidosis Vii 1 92.44 High High
Disease 3 91.60 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 85.92 High High
Arrhythmogenic Right Ventricular Dysplasia 4 67.36 Quite High
Cold Sores 2 55.36 Quite High
Sprains And Strains 2 54.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In previous studies, we have shown that a herpesvirus vector can transfer a therapeutic cellular gene (beta-glucuronidase) from peripheral sites of inoculation into the central nervous system in mice with a model neurodegenerative disease caused by a deficiency of this enzyme (mucopolysaccharidosis type VII, Sly disease).
Positive_regulation (transfer) of Gene_expression (transfer) of beta-glucuronidase in central nervous system associated with mucopolysaccharidosis vii, mucopolysaccharidoses, central nervous system and neurodegenerative disease
1) Confidence 0.34 Published 1996 Journal J. Neurovirol. Section Abstract Doc Link 8972424 Disease Relevance 0.47 Pain Relevance 0.05
A fraction containing most exclusively the sulfated polysaccharide known as ulvan-induced expression of a GUS gene placed under the control of a lipoxygenase gene promoter.
Positive_regulation (induced) of Gene_expression (expression) of GUS
2) Confidence 0.14 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Abstract Doc Link PMC2860583 Disease Relevance 0.09 Pain Relevance 0
Arrhythmias after ASD repair
Positive_regulation (after) of Gene_expression (repair) of ASD
3) Confidence 0.05 Published 2008 Journal J Interv Card Electrophysiol Section Body Doc Link PMC2493534 Disease Relevance 0.81 Pain Relevance 0

General Comments

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