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Context Info
Confidence 0.41
First Reported 1996
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.23
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (F2) peptidase activity (F2) extracellular space (F2)
extracellular region (F2) response to stress (F2)
F2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 2 97.68 Very High Very High Very High
ischemia 2 88.88 High High
Pain 1 77.84 Quite High
imagery 1 75.08 Quite High
headache 2 69.16 Quite High
Disease Link Frequency Relevance Heat
Sickle Cell Anemia 8 99.68 Very High Very High Very High
Arterial-venous Cerebral Malformations 6 99.66 Very High Very High Very High
Thrombosis 3 99.20 Very High Very High Very High
Cv General 3 Under Development 2 97.68 Very High Very High Very High
Thrombophilia 1 90.56 High High
Cerebral Edema 1 89.96 High High
Cv Unclassified Under Development 2 88.88 High High
Emergencies 1 81.28 Quite High
Coagulation Disorder 2 80.36 Quite High
Congenital Anomalies 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acute neurological decline after spontaneous thrombosis of an intracranial AVM is rare, and an association with the prothrombin defect in this patient is likely.
Negative_regulation (defect) of prothrombin Binding (association) of associated with arterial-venous cerebral malformations and thrombosis
1) Confidence 0.41 Published 2007 Journal J. Neurosurg. Section Abstract Doc Link 17330543 Disease Relevance 1.27 Pain Relevance 0.19
Inhibition of factor VIIa generation and prothrombin activation by treatment with enoxaparin in patients with unstable angina.
Negative_regulation (Inhibition) of prothrombin Binding (generation) of associated with angina
2) Confidence 0.06 Published 2003 Journal Br. J. Haematol. Section Title Doc Link 12588347 Disease Relevance 0.19 Pain Relevance 0.19
Mean levels of prothrombin complex were similar in asymptomatic patients to those in controls, but were significantly decreased during sickle cell crisis (p < 0.05 for factor V and p < 0.0001 for factors II, VII and X).
Negative_regulation (decreased) of prothrombin Binding (complex) of associated with sickle cell anemia
3) Confidence 0.03 Published 1996 Journal Hematol Cell Ther Section Abstract Doc Link 8974793 Disease Relevance 0.77 Pain Relevance 0.08

General Comments

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