INT67228

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 1996
Last Reported 2010
Negated 4
Speculated 1
Reported most in Body
Documents 11
Total Number 12
Disease Relevance 6.67
Pain Relevance 5.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il4) extracellular region (Il4)
Anatomy Link Frequency
spinal cord 4
spinal 2
plasma 2
T-helper cells 2
T cells 2
Il4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 60 99.40 Very High Very High Very High
Migraine 5 99.12 Very High Very High Very High
Eae 136 99.08 Very High Very High Very High
Thermal hyperalgesia 48 99.00 Very High Very High Very High
cytokine 148 97.72 Very High Very High Very High
Dorsal horn 48 97.40 Very High Very High Very High
dorsal root ganglion 92 96.84 Very High Very High Very High
Neuropathic pain 116 90.56 High High
withdrawal 32 90.00 High High
Pain 40 87.76 High High
Disease Link Frequency Relevance Heat
Injury 16 99.32 Very High Very High Very High
Headache 3 99.12 Very High Very High Very High
Hyperalgesia 56 99.00 Very High Very High Very High
Nociception 32 98.08 Very High Very High Very High
Cancer 14 97.92 Very High Very High Very High
Ganglion Cysts 96 96.84 Very High Very High Very High
Apoptosis 1 96.12 Very High Very High Very High
Migraine Without Aura 2 94.36 High High
Asthma 24 93.20 High High
Disease 10 92.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Vector-mediated IL-4 production did not affect normal sensory function.
Neg (not) Regulation (affect) of Gene_expression (production) of IL-4
1) Confidence 0.50 Published 2006 Journal Mol Pain Section Body Doc Link PMC1395302 Disease Relevance 1.00 Pain Relevance 0.77
Effect of S4IL4 inoculation on spinal IL-1?
Regulation (Effect) of Gene_expression (inoculation) of S4IL4 in spinal
2) Confidence 0.32 Published 2006 Journal Mol Pain Section Body Doc Link PMC1395302 Disease Relevance 0.52 Pain Relevance 0.95
Effect of S4IL4 inoculation on Fos-LI in the spinal cord
Regulation (Effect) of Gene_expression (inoculation) of S4IL4 in spinal cord associated with spinal cord
3) Confidence 0.32 Published 2006 Journal Mol Pain Section Body Doc Link PMC1395302 Disease Relevance 0.78 Pain Relevance 1.11
Effect of S4IL4 inoculation on Fos-LI in the spinal cord
Regulation (on) of Gene_expression (inoculation) of S4IL4 in spinal cord associated with spinal cord
4) Confidence 0.32 Published 2006 Journal Mol Pain Section Body Doc Link PMC1395302 Disease Relevance 0.83 Pain Relevance 1.10
This study examines the alterations in serum levels of TGF-beta and IL-4 after a thermal injury.
Spec (examines) Regulation (alterations) of Gene_expression (levels) of IL-4 associated with injury
5) Confidence 0.26 Published 2001 Journal Shock Section Abstract Doc Link 11699077 Disease Relevance 0.71 Pain Relevance 0.13
Accordingly, IL-4 production by CD4+ T cells is affected by cyclical variations of circulating estradiol levels [16,17].
Regulation (affected) of Gene_expression (production) of IL-4 in T cells
6) Confidence 0.22 Published 2010 Journal Respir Res Section Body Doc Link PMC2936382 Disease Relevance 0.80 Pain Relevance 0.05
We proposed that melatonin regulates interleukin-4 (IL-4) production in bone marrow T-helper cells and that IL-4 stimulates adherent stromal cells to produce colony stimulating factors (CSF).
Regulation (regulates) of Gene_expression (production) of interleukin-4 in T-helper cells
7) Confidence 0.18 Published 1996 Journal J. Pineal Res. Section Abstract Doc Link 8981257 Disease Relevance 0.19 Pain Relevance 0.19
There were no differences in corticosterone, IFN-gamma and IL-4 levels.
Neg (no) Regulation (differences) of Gene_expression (levels) of IL-4
8) Confidence 0.15 Published 2010 Journal Lipids Health Dis Section Abstract Doc Link 20615224 Disease Relevance 0.78 Pain Relevance 0.20
were observed among the levels of IL-4, TNF?
Regulation (observed) of Gene_expression (levels) of IL-4
9) Confidence 0.07 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2486352 Disease Relevance 0.32 Pain Relevance 0
There was not any difference with respect to IL-2/IL-4 ratio
Neg (not) Regulation (difference) of Gene_expression (ratio) of IL-4
10) Confidence 0.07 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2486352 Disease Relevance 0.30 Pain Relevance 0
In addition, we have shown that whereas IL-2 and interferon-gamma production is dramatically impaired by the drug, IL-4 production is not significantly altered.
Neg (not) Regulation (altered) of Gene_expression (production) of IL-4
11) Confidence 0.06 Published 1997 Journal Int. J. Immunopharmacol. Section Abstract Doc Link 9278182 Disease Relevance 0.08 Pain Relevance 0.19
To this end, plasma levels of IFN-gamma, IL-4, IL-5, and IL-10 were measured by enzyme-linked immunosorbent assay (ELISA) techniques.
Regulation (measured) of Gene_expression (levels) of IL-4 in plasma
12) Confidence 0.03 Published 1998 Journal Headache Section Abstract Doc Link 9664752 Disease Relevance 0.34 Pain Relevance 0.52

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox