INT67383

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Context Info
Confidence 0.00
First Reported 1996
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OPRK1, Pdyn) extracellular region (Pdyn) signal transducer activity (OPRK1)
OPRK1 (Homo sapiens)
Pdyn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dynorphin 16 100.00 Very High Very High Very High
orphanin 10 100.00 Very High Very High Very High
Kappa opioid receptor 4 100.00 Very High Very High Very High
Opioid 1 92.84 High High
Neuropeptide 2 86.88 High High
MU agonist 2 75.00 Quite High
narcan 2 25.00 Low Low
antagonist 2 25.00 Low Low
Analgesic 1 25.00 Low Low
opioid receptor 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dynorphin has long been considered the putative endogenous ligand for the kappa-opioid receptor.
kappa-opioid receptor Binding (ligand) of Dynorphin associated with dynorphin and kappa opioid receptor
1) Confidence 0.00 Published 1996 Journal Neuroendocrinology Section Abstract Doc Link 8990074 Disease Relevance 0 Pain Relevance 0.44
Replacement of as many as eleven residues in the C-terminus of dynorphin by the corresponding nociceptin sequence has no significant effect on binding and biological activity towards the kappa-opioid receptor.
kappa-opioid receptor Binding (binding) of dynorphin associated with dynorphin, orphanin and kappa opioid receptor
2) Confidence 0.00 Published 1997 Journal FEBS Lett. Section Abstract Doc Link 9409745 Disease Relevance 0 Pain Relevance 0.81

General Comments

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