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Context Info
Confidence 0.59
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.82

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mitochondrion (Aldh1l1) oxidoreductase activity (Aldh1l1) methyltransferase activity (Aldh1l1)
biosynthetic process (Aldh1l1) protein complex (Aldh1l1) cytoplasm (Aldh1l1)
Aldh1l1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 9 99.22 Very High Very High Very High
Analgesic 1 56.56 Quite High
Disease Link Frequency Relevance Heat
Toxicity 2 73.88 Quite High
Hepatotoxicity 3 70.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Administration of a toxic dose of acetaminophen (400 mg/kg) to mice resulted in a 25% decrease in cytosolic N-10-formyltetrahydrofolate dehydrogenase activity at 2 hr.
Negative_regulation (decrease) of N-10-formyltetrahydrofolate associated with paracetamol
1) Confidence 0.59 Published 1997 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 8996234 Disease Relevance 0.27 Pain Relevance 0.82

General Comments

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