INT67527

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Context Info
Confidence 0.21
First Reported 1997
Last Reported 1998
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.50
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
MRXS5 (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 3 95.84 Very High Very High Very High
Inflammation 2 90.76 High High
cytokine 3 85.88 High High
Disease Link Frequency Relevance Heat
Anaplastic Astrocytoma 3 99.52 Very High Very High Very High
Disease 9 99.20 Very High Very High Very High
INFLAMMATION 4 95.28 Very High Very High Very High
Creutzfeldt Jakob Disease 1 94.04 High High
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To assess whether PGs are able to induce IL-6 synthesis in cells of the CNS, IL-6 mRNA and protein syntheses were measured in a human astrocytoma cell line after stimulation with different PGs.
PGs Spec (whether) Positive_regulation (induce) of Gene_expression (synthesis) of IL-6 associated with anaplastic astrocytoma
1) Confidence 0.21 Published 1997 Journal J. Neurochem. Section Abstract Doc Link 9003059 Disease Relevance 0.74 Pain Relevance 0.28
Here, we show that PGs are able to induce IL-6 synthesis in a human astrocytoma cell line.
PGs Positive_regulation (induce) of Gene_expression (synthesis) of IL-6 associated with anaplastic astrocytoma
2) Confidence 0.16 Published 1998 Journal J. Neural Transm. Suppl. Section Abstract Doc Link 9850935 Disease Relevance 0.77 Pain Relevance 0.17

General Comments

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