INT67708

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Context Info
Confidence 0.32
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 3.12
Pain Relevance 1.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pecam1) cell adhesion (Pecam1) plasma membrane (Pecam1)
Anatomy Link Frequency
endothelial cell 3
Blood vessels 3
fat 1
vessels 1
Pecam1 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 10 97.52 Very High Very High Very High
Calcitonin gene-related peptide 16 96.84 Very High Very High Very High
backache 4 95.04 Very High Very High Very High
Neuropeptide 6 93.56 High High
cytokine 34 85.96 High High
ischemia 72 71.00 Quite High
Inflammation 37 59.72 Quite High
Hippocampus 16 56.36 Quite High
nociceptor 4 56.24 Quite High
Arthritis 33 41.36 Quite Low
Disease Link Frequency Relevance Heat
Adhesions 16 100.00 Very High Very High Very High
Cancer 105 99.36 Very High Very High Very High
Middle Cerebral Artery Infarction 9 98.32 Very High Very High Very High
Low Back Pain 4 95.68 Very High Very High Very High
Hypersensitivity 8 93.96 High High
Myocardial Infarction 70 92.96 High High
Necrosis 8 91.68 High High
Stroke 41 87.00 High High
Disease 43 84.76 Quite High
Infarction 5 84.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To reduce background staining, the membranes were incubated with 5% non-fat dry milk in PBS containing 0.1% Tween 20 for 45 minutes, followed by incubation with mouse anti-PECAM-1 antiserum (1 : 2,000), peroxidase-conjugated goat anti-mouse IgG (Sigma, St.
anti-PECAM-1 Binding (incubation) of in fat
1) Confidence 0.32 Published 2010 Journal Anatomy & Cell Biology Section Body Doc Link PMC2998780 Disease Relevance 0.10 Pain Relevance 0.06
 : interleukin-1beta; MCA: middle cerebral artery; min: minutes; PBS: phosphate buffered saline; PECAM: platelet endothelial cell adhesion molecule-1; PFA: paraformaldehyde; pMCAO: permanent middle cerebral artery occlusion; RT: room temperature; SB: Soerensens phosphate buffer; s.c.: subcutaneous; SSC: side scatter; TBS: tris buffered saline; TNF: tumor necrosis factor; vWF: von Willebrand factor; WT: B6.SJL-Ptprca Pepcb/BoyJ.


PECAM Binding (saline) of in endothelial cell associated with necrosis, cancer, middle cerebral artery infarction, hypersensitivity and adhesions
2) Confidence 0.27 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2585073 Disease Relevance 0.71 Pain Relevance 0.08
 : interleukin-1beta; MCA: middle cerebral artery; min: minutes; PBS: phosphate buffered saline; PECAM: platelet endothelial cell adhesion molecule-1; PFA: paraformaldehyde; pMCAO: permanent middle cerebral artery occlusion; RT: room temperature; SB: Soerensens phosphate buffer; s.c.: subcutaneous; SSC: side scatter; TBS: tris buffered saline; TNF: tumor necrosis factor; vWF: von Willebrand factor; WT: B6.SJL-Ptprca Pepcb/BoyJ.


platelet endothelial cell adhesion molecule-1 Binding (saline) of in endothelial cell associated with necrosis, cancer, middle cerebral artery infarction, hypersensitivity and adhesions
3) Confidence 0.27 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2585073 Disease Relevance 0.72 Pain Relevance 0.08
PECAM-1 has been shown to recognize only vascular endothelial cells [23].
PECAM-1 Binding (recognize) of in endothelial cells
4) Confidence 0.26 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575610 Disease Relevance 0 Pain Relevance 0
Blood vessel density in immunofluorescent stained sections from size-matched tumors was determined by counting the number of PECAM-1+/GFP?
PECAM Binding (number) of in Blood vessel associated with cancer
5) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2842301 Disease Relevance 0.15 Pain Relevance 0
Interobserver correlation coefficient for CD31+/aSMA- number of vessels was r?
CD31 Binding (coefficient) of in vessels
6) Confidence 0.23 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2779850 Disease Relevance 0 Pain Relevance 0
/CD31+) cell populations. a The amount of Sca+/CD31?
CD31 Binding (amount) of
7) Confidence 0.22 Published 2010 Journal Basic Res Cardiol Section Body Doc Link PMC2916122 Disease Relevance 0.57 Pain Relevance 0.03
Blood vessels were identified by immunoreactivity with platelet-endothelial cell-adhesion molecule (CD31; PECAM).
CD31 Binding (immunoreactivity) of in Blood vessels associated with adhesions
8) Confidence 0.14 Published 1997 Journal J Bone Joint Surg Br Section Abstract Doc Link 9020464 Disease Relevance 0.44 Pain Relevance 0.67
Blood vessels were identified by immunoreactivity with platelet-endothelial cell-adhesion molecule (CD31; PECAM).
platelet-endothelial cell-adhesion molecule Binding (immunoreactivity) of in Blood vessels associated with adhesions
9) Confidence 0.12 Published 1997 Journal J Bone Joint Surg Br Section Abstract Doc Link 9020464 Disease Relevance 0.43 Pain Relevance 0.67

General Comments

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