INT67725

Context Info Confidence 0.04 First Reported 1996 Last Reported 1996 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.09 Pain Relevance 0.28

plasma membrane (TACR1) cytoplasm (TACR1) signal transducer activity (TACR1)

TACR1 (Homo sapiens)

Pain Link Frequency Relevance Heat substance P 6 98.80 agonist 1 66.48 Potency 3 26.32 Analgesic 1 25.00

Disease Link Frequency Relevance Heat Tics 1 85.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The aim of this study was the topographical characterization of the binding subsites of human NK-1 receptor expressed in CHO cells, especially the S7 and S8 subsites, corresponding to residues Phe7 and Phe8 of substance P.

Positive_regulation (corresponding) of NK-1 Binding (binding) of associated with substance p

1) Confidence 0.04 Published 1996 Journal Bioorg. Med. Chem. Section Abstract Doc Link 9022979 Disease Relevance 0.09 Pain Relevance 0.28

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