INT67908

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Context Info
Confidence 0.04
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Plxna3) extracellular space (Cck) extracellular region (Cck)
intracellular (Plxna3)
Cck (Rattus norvegicus)
Plxna3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Endogenous opioid 2 98.64 Very High Very High Very High
Somatostatin 10 90.00 High High
Cholecystokinin 2 75.00 Quite High
antagonist 2 75.00 Quite High
MU agonist 1 75.00 Quite High
agonist 1 74.56 Quite High
Opioid 1 72.08 Quite High
Neuropeptide 1 71.04 Quite High
Intracerebroventricular 1 66.00 Quite High
Disease Link Frequency Relevance Heat
Fever 4 97.88 Very High Very High Very High
Hypothermia 2 90.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The CCK-8 (300 ng)-induced hyperthermia was blocked by pretreatment of rats with CTAP (1 microgram, i.c.v.), suggesting that the higher doses of CCK-8 increase Tb through the interaction with mu-receptors or the enhancement of release of endogenous opioids acting on the mu-receptor.
CCK-8 Binding (interaction) of mu-receptors associated with endogenous opioid and fever
1) Confidence 0.04 Published 1997 Journal Brain Res. Section Abstract Doc Link 9037404 Disease Relevance 0.54 Pain Relevance 0.84

General Comments

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