INT68014

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Context Info
Confidence 0.41
First Reported 1997
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Pnoc)
Pnoc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
orphanin 18 100.00 Very High Very High Very High
Eae 2 99.48 Very High Very High Very High
Hippocampus 3 94.60 High High
Intracerebroventricular 1 80.88 Quite High
Pain 4 78.24 Quite High
Lasting pain 3 50.00 Quite Low
Central grey 2 50.00 Quite Low
allodynia 2 50.00 Quite Low
Disease Link Frequency Relevance Heat
Pain 5 93.48 High High
Nociception 1 91.52 High High
Neuropathic Pain 2 90.92 High High
Urological Neuroanatomy 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intrahippocampal injection of nociceptin/ orphanin FQ markedly decreased exploratory locomotor activity including vertical movements (rearing).
Negative_regulation (decreased) of Gene_expression (injection) of orphanin FQ associated with eae and orphanin
1) Confidence 0.41 Published 1997 Journal Eur. J. Neurosci. Section Abstract Doc Link 9042583 Disease Relevance 0.08 Pain Relevance 0.95
In each, Nociceptin/Orphanin FQ transmission was abolished using UFP-101, a selective NOP receptor antagonist, which was injected into the vlPAG at a dose of 18 microg/1 microl/rat.
Negative_regulation (abolished) of Gene_expression (transmission) of Orphanin FQ
2) Confidence 0.41 Published 2009 Journal Life Sci. Section Body Doc Link 19523963 Disease Relevance 0.28 Pain Relevance 0

General Comments

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