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Context Info
Confidence 0.05
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pdpk1) extracellular space (Pla2g1b) extracellular region (Pla2g1b)
cytoplasmic membrane-bounded vesicle (Pdpk1) plasma membrane (Pdpk1) nucleus (Pdpk1)
Pla2g1b (Rattus norvegicus)
Pdpk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 4 100.00 Very High Very High Very High
Thermal hyperalgesia 15 99.02 Very High Very High Very High
Glutamate receptor 1 94.28 High High
nMDA receptor 5 92.08 High High
Hyperalgesia 1 74.12 Quite High
intrathecal 6 65.68 Quite High
antagonist 3 37.64 Quite Low
excitatory amino acid 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 16 99.02 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The thermal hyperalgesia produced by N-methyl-D-aspartate is mediated by activation of nitric oxide synthase and protein kinase C, but not by phospholipase C, phospholipase A2, cyclo-oxygenase or lipoxygenase.
phospholipase A2 Positive_regulation (activation) of protein kinase associated with kinase c and thermal hyperalgesia
1) Confidence 0.05 Published 1996 Journal Neuroscience Section Abstract Doc Link 9053788 Disease Relevance 0.63 Pain Relevance 1.12

General Comments

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