INT68186

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 11
Disease Relevance 6.01
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (GOT2) mitochondrion (GOT2) small molecule metabolic process (GOT2)
biosynthetic process (GOT2) plasma membrane (GOT2) carbohydrate metabolic process (GOT2)
Anatomy Link Frequency
ileum 1
myocardium 1
liver 1
GPBB 1
jejunum 1
GOT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 2 99.98 Very High Very High Very High
Angina 9 98.08 Very High Very High Very High
Inflammation 26 97.76 Very High Very High Very High
cINOD 86 97.32 Very High Very High Very High
COX-2 inhibitor 50 90.32 High High
Acupuncture 1 86.64 High High
Osteoarthritis 99 83.92 Quite High
aspirin 24 73.36 Quite High
metalloproteinase 1 43.32 Quite Low
Inflammatory response 6 39.80 Quite Low
Disease Link Frequency Relevance Heat
Hepatitis 50 100.00 Very High Very High Very High
Hepatitis A Virus Infection 2 100.00 Very High Very High Very High
Hepatitis B Virus Infection 2 99.20 Very High Very High Very High
Myocardial Infarction 32 98.88 Very High Very High Very High
Angina 7 98.08 Very High Very High Very High
INFLAMMATION 31 97.76 Very High Very High Very High
Cv General 4 Under Development 2 97.08 Very High Very High Very High
Apoptosis 8 96.52 Very High Very High Very High
Cancer 97 96.08 Very High Very High Very High
Disease 53 95.80 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the safety data reviewed by the FDA revealed that 0.85% of patients receiving lumiracoxib 100 mg for 12 months had ALT and AST elevations >3 x ULN, a rate considered to be similar to that seen with other NSAIDs (Anon. 2007).
Gene_expression (elevations) of AST associated with cinod
1) Confidence 0.65 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012431 Disease Relevance 0.28 Pain Relevance 0.35
A 10 ml venous blood sample was collected for liver functions [ALT, aspartate aminotransferase (AST), total and indirect bilirubin, alkaline phosphatase], and exclusion of acute hepatitis A and B by serological analysis [IgM anti-hepatitis A virus (HAV) (HAVAB®, M EIA, Abbott Laboratories, Diagnostics Division, Abbott Park, IL); IgM anti-hepatitis B virus (HBV) core (CORZYME®, M rDNA, Abbott Laboratories, Diagnostics Division); hepatitis B surface antigen (AUSZYME MONOCLONAL®, third generation EIA, Abbott laboratories, Diagnostics Division, Abbott Park, IL)].
Gene_expression (anti) of AST in liver associated with hepatitis b virus infection, hepatitis a virus infection and hepatitis
2) Confidence 0.65 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2605267 Disease Relevance 1.54 Pain Relevance 0.04
Among the recently proposed new markers for early AMI diagnosis: glycogen phosphorylase isoenzyme BB (GPBB), fatty acid binding protein, phosphoglyceric acid mutase isoenzyme MB, enolase isoenzyme alpha beta, S100a0, and annexin V, GPBB is the most promising because it increases as early as 1 to 4 h from chest pain onset and its early release appears to be essentially dependent on ischemic myocardial injury.
Gene_expression (promising) of fatty acid binding protein in GPBB associated with angina, injury and myocardial infarction
3) Confidence 0.30 Published 1997 Journal Crit Rev Clin Lab Sci Section Abstract Doc Link 9055056 Disease Relevance 0.99 Pain Relevance 0.32
Development of a quantitative lateral-flow assay for rapid detection of fatty acid-binding protein.
Gene_expression (detection) of acid-binding protein in lateral
4) Confidence 0.19 Published 2003 Journal J. Immunol. Methods Section Title Doc Link 12969550 Disease Relevance 0.19 Pain Relevance 0
The MIT-MANUS project was initiated in 1989 with support from the National Science Foundation.
Gene_expression (project) of MIT-MANUS
5) Confidence 0.17 Published 2004 Journal J Neuroengineering Rehabil Section Body Doc Link PMC544952 Disease Relevance 0.09 Pain Relevance 0
Next, also circulating levels of Ileal-Bile Acid Binding Protein (I-BABP), which is exclusively present in mature enterocytes of the jejunum and ileum, were assessed [23].
Gene_expression (present) of Acid Binding Protein in ileum associated with bile
6) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.33 Pain Relevance 0.10
Heart-type fatty acid-binding protein (H-FABP) is a low molecular weight cytoplasmic protein and present abundantly in the myocardium.
Gene_expression (present) of acid-binding protein in myocardium
7) Confidence 0.13 Published 2000 Journal Clin. Chem. Lab. Med. Section Abstract Doc Link 10905760 Disease Relevance 0.28 Pain Relevance 0
By

quantitative RT-PCR, levels of adipsin, fatty acid-binding protein (FABP), and

Gene_expression (levels) of acid-binding protein
8) Confidence 0.05 Published 2008 Journal PPAR Research Section Body Doc Link PMC2605846 Disease Relevance 0.86 Pain Relevance 0
Next, also circulating levels of Ileal-Bile Acid Binding Protein (I-BABP), which is exclusively present in mature enterocytes of the jejunum and ileum, were assessed [23].
Gene_expression (present) of Acid Binding Protein in jejunum associated with bile
9) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.33 Pain Relevance 0.10
For example, heart-fatty acid binding protein (H-FABP) was initially found over-expressed in postmortem compared to antemortem CSF and was validated as a potential biomarker of Creutzfeld–Jakob disease (Guillaume et al. 2003) and stroke (Zimmermann-Ivol et al. 2004).
Gene_expression (expressed) of acid binding protein in heart associated with stroke and disease
10) Confidence 0.04 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717829 Disease Relevance 0.70 Pain Relevance 0
Analysis of the more highly expressed genes revealed a significant enrichment of genes encoding for nucleic acid binding proteins in CD34+ cells (p = 1.4 × 10-24, Table 1), being predominantly of the Zinc finger family with a KRAB domain (129 members were present among the CD34-specific genes).
Gene_expression (expressed) of acid binding in finger
11) Confidence 0.01 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2901320 Disease Relevance 0.43 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox