INT68188

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Context Info
Confidence 0.75
First Reported 1997
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 5.17
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TNNI1)
Anatomy Link Frequency
cardiac muscle 1
chest 1
skeletal muscle 1
TNNI1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 9 97.08 Very High Very High Very High
analgesia 59 93.36 High High
epidural 72 92.36 High High
Angina 13 87.96 High High
Perioperative pain 2 82.88 Quite High
cerebral cortex 1 82.72 Quite High
Opioid 15 81.68 Quite High
Inflammation 4 79.52 Quite High
Analgesic 10 77.20 Quite High
anesthesia 21 65.12 Quite High
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 1 99.92 Very High Very High Very High
Neurodegenerative Disease 3 98.28 Very High Very High Very High
Coronary Artery Disease 16 97.88 Very High Very High Very High
Neck Pain 1 97.08 Very High Very High Very High
Fever 2 96.52 Very High Very High Very High
Emergencies 7 96.22 Very High Very High Very High
Myocardial Infarction 15 90.92 High High
Shock 1 90.48 High High
Pneumonia 9 90.32 High High
Pain 12 89.36 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We therefore investigated the correlation between serum S100B levels and those of the specific cardiac marker troponin I in order to assess the cerebral vs. extracerebral origin of S100B.
Gene_expression (levels) of troponin I
1) Confidence 0.75 Published 2004 Journal Anaesthesia Section Abstract Doc Link 15023104 Disease Relevance 0.08 Pain Relevance 0.07
We obtained troponin I levels 6 to 12 hours postoperatively and on the first, second, and third day after surgery.
Gene_expression (levels) of troponin I
2) Confidence 0.65 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2645707 Disease Relevance 1.21 Pain Relevance 1.00
In the judgment of the attending emergency physician (EP), these patientsÂ’ presentations warranted diagnostic testing for CAD (initial and six-hour ECG, initial chest radiography, and initial and six-hour creatine phosphokinase-MB fraction and Troponin I) but were all negative.
Gene_expression (fraction) of Troponin I in chest associated with coronary artery disease, emergencies and disorders of creatine metabolism
3) Confidence 0.65 Published 2010 Journal Western Journal of Emergency Medicine Section Body Doc Link PMC2967693 Disease Relevance 1.90 Pain Relevance 0.14
In particular, we have analyzed the expression levels of TNN1C (troponin C type 1) mRNA, a stable gene expressed in the skeletal muscle.
Spec (analyzed) Gene_expression (expression) of TNN1C in skeletal muscle
4) Confidence 0.13 Published 2010 Journal Genome Biol Section Body Doc Link PMC2847721 Disease Relevance 0.24 Pain Relevance 0.04
Laboratory data on admission revealed elevated serum levels of CRP, GOT, GPT, LDH, CK, and troponin-I with hypo gamma-globulinemia.
Gene_expression (levels) of troponin-I
5) Confidence 0.05 Published 2010 Journal Nihon Kokyuki Gakkai Zasshi Section Abstract Doc Link 20608087 Disease Relevance 0.87 Pain Relevance 0.14
By contrast, the regulatory proteins troponin I and troponin T are expressed in three different isoforms: one for slow-twitch skeletal muscle fibers, one for fast-twitch skeletal muscle fibers, and one for cardiac muscle (cTnI, cTnT); cardiac-specific cTnI and cTnT assays are already available for routine use. cTnT and cTnI are the most promising markers for risk stratification in patients with unstable angina pectoris.
Gene_expression (expressed) of troponin I in cardiac muscle associated with angina
6) Confidence 0.03 Published 1997 Journal Crit Rev Clin Lab Sci Section Abstract Doc Link 9055056 Disease Relevance 0.88 Pain Relevance 0.34

General Comments

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