INT68189

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Context Info
Confidence 0.75
First Reported 1997
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 27
Total Number 28
Disease Relevance 14.87
Pain Relevance 4.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TNNT1)
Anatomy Link Frequency
autonomic 3
Plasma 2
ZFL 2
coronary artery 1
cardiac muscle 1
TNNT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 57 100.00 Very High Very High Very High
ischemia 99 98.80 Very High Very High Very High
Catecholamine 188 97.20 Very High Very High Very High
depression 4 95.04 Very High Very High Very High
Inflammation 35 93.68 High High
aspirin 167 93.08 High High
Pain 12 91.40 High High
abdominal pain 1 91.32 High High
cytokine 32 89.56 High High
Dopamine 16 84.64 Quite High
Disease Link Frequency Relevance Heat
Myocardial Infarction 172 100.00 Very High Very High Very High
Acute Coronary Syndrome 125 100.00 Very High Very High Very High
Cv General 3 Under Development 33 100.00 Very High Very High Very High
Urological Neuroanatomy 22 100.00 Very High Very High Very High
Fever 9 100.00 Very High Very High Very High
Cv General 2 Under Development 6 100.00 Very High Very High Very High
Anaerobic Bacterial Infections 204 99.92 Very High Very High Very High
Hypothermia 43 99.78 Very High Very High Very High
Coronary Artery Disease 71 99.76 Very High Very High Very High
Diabetes Mellitus 4 99.54 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By contrast, the regulatory proteins troponin I and troponin T are expressed in three different isoforms: one for slow-twitch skeletal muscle fibers, one for fast-twitch skeletal muscle fibers, and one for cardiac muscle (cTnI, cTnT); cardiac-specific cTnI and cTnT assays are already available for routine use. cTnT and cTnI are the most promising markers for risk stratification in patients with unstable angina pectoris.
Gene_expression (expressed) of troponin T in cardiac muscle associated with angina
1) Confidence 0.75 Published 1997 Journal Crit Rev Clin Lab Sci Section Abstract Doc Link 9055056 Disease Relevance 0.88 Pain Relevance 0.34
Serum troponin T, creatinine kinase-MB, and myoglobin levels were measured.
Gene_expression (levels) of troponin T
2) Confidence 0.75 Published 2008 Journal J Clin Anesth Section Body Doc Link 18761242 Disease Relevance 0.07 Pain Relevance 0
However, a coronary angiogram demonstrated minimal coronary artery disease, and serum troponin T was undetectable in serial serum measurements.
Gene_expression (undetectable) of troponin T in coronary artery associated with coronary artery disease
3) Confidence 0.75 Published 2003 Journal Pancreatology Section Abstract Doc Link 14730176 Disease Relevance 0.88 Pain Relevance 0.13
RESULTS: Results were expressed as the median, range and standard deviation (SD) of TnT concentration (microg/l).
Gene_expression (expressed) of TnT
4) Confidence 0.66 Published 1998 Journal J Cardiovasc Surg (Torino) Section Body Doc Link 9972901 Disease Relevance 0 Pain Relevance 0
Logistic regression was used to assess the usefulness of baseline levels of troponin T and CK-MB vs.
Gene_expression (levels) of troponin T
5) Confidence 0.65 Published 2008 Journal Int J Emerg Med Section Body Doc Link PMC2657250 Disease Relevance 0.48 Pain Relevance 0.25
However, ADP levels did not correlate with either CKMB or troponin T levels.
Gene_expression (levels) of troponin T
6) Confidence 0.65 Published 2005 Journal Thromb J Section Body Doc Link PMC1192820 Disease Relevance 0.69 Pain Relevance 0.44
For purine measurements there were no significant correlation with age, diabetes, haemoglobin, CKMB or troponin T levels.
Gene_expression (levels) of troponin T associated with diabetes mellitus
7) Confidence 0.65 Published 2005 Journal Thromb J Section Body Doc Link PMC1192820 Disease Relevance 0.28 Pain Relevance 0.16
Cardiogenic shock as a complication of acute mitral valve regurgitation following posteromedial papillary muscle infarction in the absence of coronary artery disease

A 48 year old man was transferred to our department with cardiogenic shock, pyrexia, a high white cell count and significant serum troponin T level.

Gene_expression (transferred) of troponin T in Cardiogenic associated with coronary artery disease, mitral valve insufficiency, cv general 2 under development, fever and infarction
8) Confidence 0.65 Published 2008 Journal J Cardiothorac Surg Section Title Doc Link PMC2586022 Disease Relevance 1.12 Pain Relevance 0
Troponin T levels
Gene_expression (levels) of Troponin T
9) Confidence 0.65 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1434771 Disease Relevance 0.94 Pain Relevance 0.17
Animals treated with hypothermia had lower troponin T levels (p<0.01), reduced infarct size (34±7 versus 57±12%; p<0.05) and improved left ventricular function compared to normothermia (p<0.05).
Gene_expression (levels) of troponin T associated with hypothermia
10) Confidence 0.65 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2764338 Disease Relevance 1.55 Pain Relevance 0.19
Troponin T levels during autonomic instability
Gene_expression (levels) of Troponin T in autonomic
11) Confidence 0.65 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1434771 Disease Relevance 0.14 Pain Relevance 0.19
In all 40 cases, troponin T levels were in the normal range at all time points studied.
Gene_expression (levels) of troponin T
12) Confidence 0.65 Published 2008 Journal J Clin Anesth Section Body Doc Link 18761242 Disease Relevance 0.06 Pain Relevance 0
Serum troponin T, creatinine kinase-MB, and myoglobin levels were measured.
Gene_expression (levels) of troponin T
13) Confidence 0.65 Published 2008 Journal J Clin Anesth Section Body Doc Link 18761242 Disease Relevance 0.07 Pain Relevance 0
We investigated the use of a new, commercially available GPBB ELISA assay in 61 patients presenting with an acute coronary syndrome (37 acute myocardial infarction, 24 unstable angina pectoris) in comparison to established cardiac markers such as troponin T, creatine kinase isoenzyme MB (CKMB) mass, and myoglobin.
Gene_expression (presenting) of troponin T associated with acute coronary syndrome, angina and myocardial infarction
14) Confidence 0.65 Published 2005 Journal Clin. Chem. Lab. Med. Section Abstract Doc Link 16309372 Disease Relevance 0.61 Pain Relevance 0.34
Usefulness of positive troponin-T and negative creatine kinase levels in identifying high-risk patients with unstable angina pectoris.
Gene_expression (Usefulness) of troponin-T associated with angina
15) Confidence 0.65 Published 1997 Journal Am. J. Cardiol. Section Title Doc Link 9285668 Disease Relevance 0.38 Pain Relevance 0.29
Plasma levels of Troponin T were analysed using the Elecsys immunoassay system (Roche Diagnostics Scandinavia, Bromma, Sweden).
Spec (analysed) Gene_expression (levels) of Troponin T in Plasma
16) Confidence 0.58 Published 2010 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2955599 Disease Relevance 0 Pain Relevance 0.03
Elevated values of troponin T detected during autonomic instability were not associated with left ventricular dysfunction.
Gene_expression (detected) of troponin T in autonomic associated with left ventricular dysfunction
17) Confidence 0.58 Published 2006 Journal J Negat Results Biomed Section Abstract Doc Link PMC1434771 Disease Relevance 0.64 Pain Relevance 0.16
The maximum levels of troponin-T and CK-MB were 7.0 ± 5.6 ?
Gene_expression (levels) of troponin-T
18) Confidence 0.58 Published 2010 Journal J Cardiovasc Magn Reson Section Body Doc Link PMC2885384 Disease Relevance 0.10 Pain Relevance 0.14
Levels of the troponin T were used to identify potential myocardial damage in the period of autonomic instability.
Gene_expression (Levels) of troponin T in autonomic
19) Confidence 0.58 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1434771 Disease Relevance 0.87 Pain Relevance 0.27
Comparison with levels of CK, CKMB, CKMB mass and troponin T in the diagnosis of coronary ischemia].
Gene_expression (levels) of troponin T associated with ischemia
20) Confidence 0.58 Published 1997 Journal Vnitr Lek Section Title Doc Link 9650501 Disease Relevance 0.44 Pain Relevance 0.29

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