INT68216

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Context Info
Confidence 0.48
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 40
Total Number 40
Disease Relevance 51.24
Pain Relevance 4.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (NF1) signal transduction (NF1) nucleus (NF1)
intracellular (NF1) extracellular matrix organization (NF1) cytoplasm (NF1)
Anatomy Link Frequency
NF-1 6
subclavian artery 4
vertebral artery 2
nervous system 2
tibia 1
NF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Peripheral nervous system 1 100.00 Very High Very High Very High
Central nervous system 20 99.76 Very High Very High Very High
cva 28 99.14 Very High Very High Very High
abdominal pain 4 98.08 Very High Very High Very High
nud 1 97.44 Very High Very High Very High
headache 18 96.08 Very High Very High Very High
Spinal cord 6 94.96 High High
Angina 3 92.00 High High
Pain 42 91.52 High High
fifth nerve 2 87.96 High High
Disease Link Frequency Relevance Heat
Watson Syndrome 376 100.00 Very High Very High Very High
Disease 252 100.00 Very High Very High Very High
Stress 119 100.00 Very High Very High Very High
Neurofibromatosis 53 100.00 Very High Very High Very High
Nerve Sheath Neoplasms 92 99.98 Very High Very High Very High
Aneurism 32 99.98 Very High Very High Very High
Sarcoma 26 99.98 Very High Very High Very High
Glioma 12 99.98 Very High Very High Very High
Gliosarcoma 7 99.98 Very High Very High Very High
Cleidocranial Dysplasia 37 99.96 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neurofibromas are generally well-circumscribed tumors of the nervous system, often found in association with neurofibromatosis 1 (NF1).
NF1 Binding (association) of in nervous system associated with nervous system cancer, watson syndrome and neurofibroma
1) Confidence 0.48 Published 2008 Journal J Hepatobiliary Pancreat Surg Section Abstract Doc Link 18535773 Disease Relevance 0.68 Pain Relevance 0.12
This patient was unnecessarily investigated for NF1 because of its association with congenital anterolateral bowing of the tibia.
NF1 Binding (association) of in tibia associated with watson syndrome
2) Confidence 0.48 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC1948010 Disease Relevance 1.06 Pain Relevance 0.10
Treatment should be started as quickly as possible if the tumor is associated with NF-1, because of the poor prognosis associated with this condition.
NF-1 Binding (associated) of in NF-1 associated with cancer and watson syndrome
3) Confidence 0.48 Published 2004 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 14959936 Disease Relevance 1.28 Pain Relevance 0.23
It is well known that von Recklinghausen's disease (NF-1) is often associated with optic glioma (5-36%).
NF-1 Binding (associated) of in optic associated with optic nerve glioma and disease
4) Confidence 0.48 Published 1997 Journal No Shinkei Geka Section Abstract Doc Link 9058438 Disease Relevance 1.96 Pain Relevance 0.23
The prognosis of supratentorial glioma associated with NF-1 was poor in these reports.
NF-1 Binding (associated) of in NF-1 associated with disease and glioma
5) Confidence 0.48 Published 1997 Journal No Shinkei Geka Section Abstract Doc Link 9058438 Disease Relevance 1.68 Pain Relevance 0.20
We described a dissecting aneurysm of the vertebral artery (VA), which was associated with neurofibromatosis type 1 (NF1).
NF1 Binding (associated) of in vertebral artery associated with dissecting aneurysm and watson syndrome
6) Confidence 0.48 Published 1999 Journal No Shinkei Geka Section Abstract Doc Link 10535082 Disease Relevance 1.19 Pain Relevance 0.28
Intracranial dissection is rarely reported in association with NF1.
NF1 Binding (association) of associated with watson syndrome
7) Confidence 0.48 Published 1999 Journal No Shinkei Geka Section Abstract Doc Link 10535082 Disease Relevance 1.57 Pain Relevance 0.28
Our patient is one of the extremely rare cases of cardiac metastasis of MPNST associated with NF1.
NF1 Binding (associated) of associated with nerve sheath neoplasms, watson syndrome and metastasis
8) Confidence 0.48 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2881068 Disease Relevance 2.02 Pain Relevance 0
Gastrointestinal lesions associated with NF-1, although usually asymptomatic, may present as abdominal pain, dyspepsia, vomiting, anaemia, melaena, haematemesis, haematochezia, intussusception, volvulus, small bowel obstruction, fever and abdominal mass.
NF-1 Binding (associated) of in bowel associated with abdominal pain, intestinal obstruction, intestinal volvulus, vomiting, nud, fever, watson syndrome, anaemia and intussusception
9) Confidence 0.43 Published 2004 Journal World J Surg Oncol Section Body Doc Link PMC317374 Disease Relevance 2.77 Pain Relevance 0.15
Measures of morbidity associated with NF1-CTD should be comparable with data on norms from surveys of general populations and other patient groups, and be useful for assessing the effectiveness and efficiency of health care services.


NF1 Binding (associated) of associated with cleidocranial dysplasia and watson syndrome
10) Confidence 0.42 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC548287 Disease Relevance 0.35 Pain Relevance 0
We described a dissecting aneurysm of the vertebral artery (VA), which was associated with neurofibromatosis type 1 (NF1).
neurofibromatosis type 1 Binding (associated) of in vertebral artery associated with dissecting aneurysm and watson syndrome
11) Confidence 0.42 Published 1999 Journal No Shinkei Geka Section Abstract Doc Link 10535082 Disease Relevance 1.19 Pain Relevance 0.28
Pulmonary sarcoma complicated with neurofibromatosis type 1 (NF1).
NF1 Binding (complicated) of associated with sarcoma and watson syndrome
12) Confidence 0.37 Published 2003 Journal Anticancer Res. Section Title Doc Link 12680156 Disease Relevance 1.32 Pain Relevance 0.09
Neurofibromatosis type 1 (NF1), also known as von Recklinghausen's disease, is the most common type of NF and accounts for about 90% of all cases.
NF1 Binding (accounts) of associated with neurofibromatosis, disease and watson syndrome
13) Confidence 0.37 Published 2004 Journal Br Dent J Section Abstract Doc Link 15105854 Disease Relevance 1.14 Pain Relevance 0.06
NF1 can also present with central nervous system (CNS) tumors which is why neuroimaging studies may be performed even though some recommend that neuroimaging should not be performed routinely [4].
NF1 Binding (present) of in central nervous system associated with cancer, central nervous system and watson syndrome
14) Confidence 0.37 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC1948010 Disease Relevance 1.19 Pain Relevance 0.10
We report a case of adrenal PHEO in a patient with NF1.
NF1 Binding (patient) of associated with watson syndrome and pheochromocytoma
15) Confidence 0.37 Published 2007 Journal J. Endocrinol. Invest. Section Abstract Doc Link 17318024 Disease Relevance 1.18 Pain Relevance 0.07
NF1 primarily affects the peripheral nervous system and is often characterized by large numbers of neurofibromas.
NF1 Binding (characterized) of in peripheral nervous system associated with peripheral nervous system, watson syndrome and neurofibroma
16) Confidence 0.37 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2823760 Disease Relevance 1.56 Pain Relevance 0.05
The histological diagnosis was MPNST developed on a background of NF1, and he received adjuvant chemotherapy.
NF1 Binding (background) of associated with nerve sheath neoplasms and watson syndrome
17) Confidence 0.37 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2881068 Disease Relevance 1.97 Pain Relevance 0
Patient with NF1 have been reported to be either sensitive or resistant to succinylcholine.
NF1 Binding (Patient) of associated with watson syndrome
18) Confidence 0.37 Published 2010 Journal Patient Saf Surg Section Body Doc Link PMC2904278 Disease Relevance 1.70 Pain Relevance 0.42
alterations in NF1 led to our hypothesis that pirfenidone might
NF1 Binding (alterations) of
19) Confidence 0.37 Published 2004 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC548804 Disease Relevance 1.01 Pain Relevance 0.07
development of neurofibromas in NF1 is still incomplete,
NF1 Binding (incomplete) of associated with neurofibroma
20) Confidence 0.37 Published 2004 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC548804 Disease Relevance 0.99 Pain Relevance 0.07

General Comments

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