INT68340

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Context Info
Confidence 0.25
First Reported 1997
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.28
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
body 1
DEC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 57.20 Quite High
Chronic pancreatitis 3 44.92 Quite Low
cytokine 7 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 50 100.00 Very High Very High Very High
Pancreatic Cancer 81 99.60 Very High Very High Very High
Disease 5 97.10 Very High Very High Very High
Dysphagia 6 96.84 Very High Very High Very High
Cancer 77 79.20 Quite High
Angina 1 57.20 Quite High
Pancreatitis 3 44.92 Quite Low
Metastasis 25 5.00 Very Low Very Low Very Low
Adenocarcinoma 10 5.00 Very Low Very Low Very Low
Solid Tumor 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results marked the first evidence that DEC1 and hexokinase II were hypoxia-induced in human pancreatic cancer and represented the initial report of hypoxic-regulation of GPI/NLK/AMF in any human system [44].
Positive_regulation (induced) of DEC1 associated with hypoxia and pancreatic cancer
1) Confidence 0.25 Published 2003 Journal Mol Cancer Section Body Doc Link PMC150383 Disease Relevance 1.58 Pain Relevance 0
Achalasia is a disease of undertermined etiology characterized by a defect in the innervation of esophageal smooth muscle causing aperistalsis of the esophageal body, increased lower esophageal sphnicter (LES) tone and inappropriate relaxation of the LES during swallowing.
Positive_regulation (increased) of esophageal sphnicter in body associated with disease and dysphagia
2) Confidence 0.00 Published 1997 Journal J Fla Med Assoc Section Abstract Doc Link 9066235 Disease Relevance 0.70 Pain Relevance 0.06

General Comments

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