INT684

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Context Info
Confidence 0.48
First Reported 1978
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 38
Total Number 40
Disease Relevance 13.90
Pain Relevance 8.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (AVP) cell-cell signaling (AVP) response to stress (AVP)
signal transducer activity (AVP) cytosol (AVP) extracellular space (AVP)
Anatomy Link Frequency
plasma 5
uterus 3
shell 2
ducts 2
myometrium 1
AVP (Homo sapiens)
Pain Link Frequency Relevance Heat
amygdala 15 100.00 Very High Very High Very High
opiate 11 100.00 Very High Very High Very High
Dopamine 10 100.00 Very High Very High Very High
Ventral tegmentum 9 100.00 Very High Very High Very High
Pain 23 99.90 Very High Very High Very High
Regional anesthesia 2 99.90 Very High Very High Very High
nociceptor 2 99.90 Very High Very High Very High
carbamazepine 4 99.84 Very High Very High Very High
monoamine 1 99.84 Very High Very High Very High
cva 43 99.82 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hyponatremia 329 100.00 Very High Very High Very High
Syndrome 33 99.64 Very High Very High Very High
Pain 31 99.60 Very High Very High Very High
Stress 95 99.52 Very High Very High Very High
Pressure And Volume Under Development 47 99.32 Very High Very High Very High
Asphyxia 2 98.88 Very High Very High Very High
Disease 34 98.84 Very High Very High Very High
Hypoglycemia 9 98.82 Very High Very High Very High
Vomiting 36 98.44 Very High Very High Very High
Cv Unclassified Under Development 4 98.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interaction of vasopressin and prostaglandin on myometrial activity in vivo in the first trimester of human pregnancy.
vasopressin Binding (Interaction) of
1) Confidence 0.48 Published 1980 Journal Br J Obstet Gynaecol Section Title Doc Link 7362800 Disease Relevance 0.24 Pain Relevance 0.09
The interaction of vasopressin (VP) and prostaglandin (PG) F2 alpha on myometrial activity was studied by intrauterine pressure recording in 40 women due to undergo therapeutic abortion in the first trimester.
VP Binding (interaction) of associated with spontaneous abortion and dismenorea
2) Confidence 0.48 Published 1980 Journal Br J Obstet Gynaecol Section Abstract Doc Link 7362800 Disease Relevance 0.19 Pain Relevance 0.10
Interaction of vasopressin and prostaglandins in the nonpregnant human uterus.
vasopressin Binding (Interaction) of in uterus
3) Confidence 0.47 Published 1984 Journal Prostaglandins Section Title Doc Link 6587440 Disease Relevance 0.12 Pain Relevance 0.12
The interaction of vasopressin (VP) and prostaglandins (PG) on the nonpregnant human uterus was studied in vitro and in vivo.
VP Binding (interaction) of in uterus
4) Confidence 0.47 Published 1984 Journal Prostaglandins Section Abstract Doc Link 6587440 Disease Relevance 0 Pain Relevance 0
These linkage relationships establish that the secretory and transcriptional associations of ARVP and PDYN extend to a close physical relationship in the human genome.
ARVP Binding (associations) of
5) Confidence 0.46 Published 1990 Journal Mol. Endocrinol. Section Abstract Doc Link 1978246 Disease Relevance 0 Pain Relevance 0
Conivaptan inhibits AVP by competitively and reversibly binding to selected AVP receptors without interacting with the receptors’s active sites.
AVP Binding (binding) of
6) Confidence 0.44 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.34 Pain Relevance 0.13
In order to establish whether ethanol exerts its inhibiting effect on the nicotine-induced release of arginine-vasopressin (AVP) by interacting with an opioid pathway, six normal volunteers were treated with naloxone (2 or 4 mg as IV bolus, plus 5 or 10 mg infused over 105 minutes) during (2 nonfilter) cigarette smoking and ethanol (50 mL to 110 mL of whiskey) drinking.
AVP Binding (interacting) of associated with nicotine addiction, nicotine, narcan and opioid
7) Confidence 0.37 Published 1987 Journal Metab. Clin. Exp. Section Abstract Doc Link 3600293 Disease Relevance 0.25 Pain Relevance 0.43
The interaction of vasopressin (VP) and prostaglandin (PG) F2 alpha on myometrial activity was studied by intrauterine pressure recording in 40 women due to undergo therapeutic abortion in the first trimester.
vasopressin Binding (interaction) of associated with spontaneous abortion and dismenorea
8) Confidence 0.37 Published 1980 Journal Br J Obstet Gynaecol Section Abstract Doc Link 7362800 Disease Relevance 0.19 Pain Relevance 0.10
The present study was carried out in order to determine whether insulin-induced hypoglycemia exerts its stimulatory effect on plasma concentrations of arginine vasopressin (AVP) by interacting with a serotonergic, a GABA-ergic or an opioid pathway.
AVP Binding (interacting) of in plasma associated with hypoglycemia, gaba and opioid
9) Confidence 0.37 Published 1988 Journal J. Endocrinol. Invest. Section Abstract Doc Link 2846678 Disease Relevance 0.17 Pain Relevance 0.53
In addition, vasopressin is functionally linked to monoamine neurotransmitter systems and, like them, is altered by pharmacological agents which affect mood.
vasopressin Binding (linked) of associated with neurotransmitter and monoamine
10) Confidence 0.37 Published 1978 Journal Lancet Section Abstract Doc Link 77997 Disease Relevance 0.46 Pain Relevance 0.27
If these findings are supported by further investigations with human subjects, various manipulations of pituitary-adrenal function, such as the administration of corticotropin and vasopressin analogs or drugs such as dexamethasone, may prove to be of clinical utility.
vasopressin Binding (administration) of in pituitary associated with dexamethasone
11) Confidence 0.37 Published 1980 Journal Med. Hypotheses Section Abstract Doc Link 6256614 Disease Relevance 0.09 Pain Relevance 0.46
The interaction of vasopressin (VP) and prostaglandins (PG) on the nonpregnant human uterus was studied in vitro and in vivo.
vasopressin Binding (interaction) of in uterus
12) Confidence 0.37 Published 1984 Journal Prostaglandins Section Abstract Doc Link 6587440 Disease Relevance 0 Pain Relevance 0
Clinical experience with arginine vasopressin (DDAVP) in von Willebrand's disease and mild haemophilia.
arginine vasopressin Binding (experience) of associated with coagulation disorder, cva and disease
13) Confidence 0.36 Published 1980 Journal N. Z. Med. J. Section Title Doc Link 6970907 Disease Relevance 0.69 Pain Relevance 0.13
[The role of arginine vasopressin (AVP) in pain transmission and perception].
arginine vasopressin Binding (role) of associated with pain and nociceptor
14) Confidence 0.36 Published 2001 Journal Postepy Hig Med Dosw Section Title Doc Link 11875780 Disease Relevance 0.19 Pain Relevance 0.49
The present study was carried out in order to determine whether insulin-induced hypoglycemia exerts its stimulatory effect on plasma concentrations of arginine vasopressin (AVP) by interacting with a serotonergic, a GABA-ergic or an opioid pathway.
arginine vasopressin Binding (interacting) of in plasma associated with hypoglycemia, gaba and opioid
15) Confidence 0.36 Published 1988 Journal J. Endocrinol. Invest. Section Abstract Doc Link 2846678 Disease Relevance 0.17 Pain Relevance 0.53
These responses are similar to those associated with arginine vasopressin (AVP) and adrenocorticotropin (ACTH) to the extent that all hormones rise in response to motion sickness (p < 0.003).
arginine vasopressin Binding (associated) of associated with vomiting
16) Confidence 0.36 Published 1992 Journal Aviat Space Environ Med Section Abstract Doc Link 1332670 Disease Relevance 0.50 Pain Relevance 0
These responses are similar to those associated with arginine vasopressin (AVP) and adrenocorticotropin (ACTH) to the extent that all hormones rise in response to motion sickness (p < 0.003).
AVP Binding (associated) of associated with vomiting
17) Confidence 0.35 Published 1992 Journal Aviat Space Environ Med Section Abstract Doc Link 1332670 Disease Relevance 0.50 Pain Relevance 0
It was suggested that the agent acts as a pharmacologic chaperone to improve trafficking of the mutated misfolded V2 receptors to the cell surface where they can interact with AVP to enhance free water retention (Bernier et al 2006).
AVP Binding (interact) of associated with pressure and volume under development
18) Confidence 0.33 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 1.00 Pain Relevance 0.14
Binding of circulating AVP to the G-protein-coupled V2 receptors on the basolateral membranes of principal cells in the collecting ducts activates adenylyl cyclase, thereby enhances the production of cyclic adenosine monophosphate (cAMP) and the subsequent activation of protein kinase A.
AVP Binding (Binding) of in ducts associated with adenocard
19) Confidence 0.33 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.54 Pain Relevance 0.32
[Changes induced by carbamazepine in the action of ADH (antidiuretic hormone) in neurologic patients].
ADH Binding (action) of associated with carbamazepine
20) Confidence 0.32 Published 1988 Journal Riv Neurol Section Title Doc Link 3175459 Disease Relevance 0.19 Pain Relevance 0.28

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