INT68420

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.53
First Reported 1997
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 0.27
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (LPAR4) plasma membrane (LPAR4) signal transducer activity (LPAR4)
Anatomy Link Frequency
A15 1
NG108-15 1
LPAR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 7 70.64 Quite High
Opioid 4 69.96 Quite High
Neurotransmitter 3 65.60 Quite High
agonist 37 61.20 Quite High
Dopamine 10 59.28 Quite High
Serotonin 3 58.40 Quite High
Cannabinoid receptor 1 48.00 Quite Low
Clonidine 6 33.44 Quite Low
dopamine receptor 6 24.24 Low Low
adenocard 1 9.92 Low Low
Disease Link Frequency Relevance Heat
Shock 6 80.04 Quite High
Stress 3 74.04 Quite High
Bordatella Infection 15 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Exencephaly /

Neural Tube Defects

9 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Wound Healing 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Spinal Injuries 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fluorescence in situ hybridization (FISH) was used to map GPR20 to chromosome 8q, region 24.3-24.2, GPR21 to chromosome 9, region q33, GPR22 to chromosome 7, region q22-q31.1, and GPR23 to chromosome X, region q13-q21.1.
Gene_expression (map) of GPR23
1) Confidence 0.53 Published 1997 Journal Gene Section Abstract Doc Link 9073069 Disease Relevance 0 Pain Relevance 0.11
The orphans P2Y5, P2Y9 and P2Y10 receptors were not placed in group 11 and 12 like most P2Y receptors, but in group A15, supporting the fact that they were misnamed.
Neg (not) Gene_expression (placed) of P2Y9 in A15
2) Confidence 0.41 Published 2002 Journal Genome Biol Section Body Doc Link PMC133447 Disease Relevance 0 Pain Relevance 0.06
In NIE-115 and NG108-15 cells, and B103 cells expressing either LPA1 or LPA4, LPA causes a rapid, transient rounding which initiates at 5 minutes following LPA addition, and cells recover their flattened morphology after 20 minutes, even in the continued presence of LPA [21,44].
Gene_expression (expressing) of LPA4 in NG108-15
3) Confidence 0.38 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2621239 Disease Relevance 0.15 Pain Relevance 0
Expression of LPA4 and 5 mRNA transcripts were relatively unchanged between the two populations.
Gene_expression (Expression) of LPA4
4) Confidence 0.38 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2621239 Disease Relevance 0 Pain Relevance 0.09
Similarly, in B103 cells expressing exogenous LPA4, but not LPA1, LPA stimulated a slow aggregation that peaked at three hours [44].
Neg (not) Gene_expression (expressing) of LPA4
5) Confidence 0.38 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2621239 Disease Relevance 0.12 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox