INT68467

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Context Info
Confidence 0.05
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pdpk1) cytoplasmic membrane-bounded vesicle (Pdpk1) plasma membrane (Pdpk1)
nucleus (Pdpk1) kinase activity (Pdpk1) cytoplasm (Pdpk1)
Pdpk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 9 100.00 Very High Very High Very High
nMDA receptor antagonist 4 100.00 Very High Very High Very High
narcan 5 99.54 Very High Very High Very High
addiction 1 89.24 High High
Kinase C 3 67.68 Quite High
Neurotransmitter 1 64.64 Quite High
medulla 1 58.56 Quite High
Hippocampus 1 56.00 Quite High
Glutamate receptor 1 38.64 Quite Low
antagonist 1 37.12 Quite Low
Disease Link Frequency Relevance Heat
Morphine Dependence 1 89.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present experiments, we studied (1) the possible role of protein kinases in the increased norepinephrine release occurring after naloxone injection and (2) the effects of NMDA receptor antagonists on chronic morphine exposure-induced changes in protein kinase activity.
Regulation (effects) of Regulation (changes) of protein kinase associated with nmda receptor antagonist, narcan and morphine
1) Confidence 0.05 Published 1997 Journal J Toxicol Sci Section Abstract Doc Link 9076657 Disease Relevance 0.09 Pain Relevance 0.96

General Comments

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