INT68500

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Context Info
Confidence 0.27
First Reported 1996
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 4.16
Pain Relevance 1.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ar) enzyme binding (Ar) DNA binding (Ar)
transcription factor binding (Ar) cytoplasm (Ar)
Anatomy Link Frequency
neurons 1
preoptic area 1
Ar (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 3 99.86 Very High Very High Very High
opiate 2 99.16 Very High Very High Very High
Inflammation 5 98.00 Very High Very High Very High
conotoxin 1 97.58 Very High Very High Very High
opioid receptor 1 94.44 High High
Dopamine 1 89.80 High High
Neurotransmitter 2 88.20 High High
antagonist 1 86.04 High High
gABA 2 85.60 High High
Migraine 4 82.80 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 1 99.96 Very High Very High Very High
Urological Neuroanatomy 2 99.80 Very High Very High Very High
Stress 92 99.70 Very High Very High Very High
Reprotox - General 1 30 98.20 Very High Very High Very High
INFLAMMATION 5 98.00 Very High Very High Very High
Disease 7 96.12 Very High Very High Very High
Neurological Disease 1 94.48 High High
Myasthenia Gravis 1 92.08 High High
Motor Neuron Diseases 2 91.96 High High
Congenital Myasthenic Syndromes 1 90.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest, on the one hand, that sexual exhaustion and the postejaculatory interval (which is shortened by bicuculline administration) are not mediated by similar mechanisms and, on the other, that the medial preoptic area does not regulate sexual satiety. (5) The androgen receptor density in brain areas closely related to the expression of masculine sexual behavior, such as the medial preoptic nucleus, was drastically reduced in sexually exhausted animals.
Neg (not) Regulation (regulate) of androgen receptor in preoptic area associated with urological neuroanatomy
1) Confidence 0.27 Published 2003 Journal Scand J Psychol Section Abstract Doc Link 12914589 Disease Relevance 0.19 Pain Relevance 0.23
Intra-prostatic OS, a phenomenon regulated via androgen receptor mediated pathways [7], is a prime target of PC prevention strategies [2], [11].
Regulation (regulated) of androgen receptor associated with stress and reprotox - general 1
2) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3011012 Disease Relevance 0.92 Pain Relevance 0.09
Cyproterone acetate increases dopaminergic responses and binds to opiate receptors independently of its classical effect on the androgen receptor.
Regulation (effect) of androgen receptor associated with opiate
3) Confidence 0.18 Published 2003 Journal Maturitas Section Abstract Doc Link 14670648 Disease Relevance 0.35 Pain Relevance 0.60
This mutation probably affects the transcription regulating activity of the androgen receptor in neurons.
Regulation (affects) of androgen receptor in neurons
4) Confidence 0.07 Published 1996 Journal Nervenarzt Section Abstract Doc Link 9082189 Disease Relevance 1.08 Pain Relevance 0.03
The review also covers in vitro studies that reveal the cell cycle specificity, induction of apoptosis, effects on androgen receptor and other molecular and metabolic changes induced by PC SPES that may explain its anticancer activity.
Regulation (effects) of androgen receptor associated with apoptosis
5) Confidence 0.01 Published 2000 Journal Int. J. Oncol. Section Abstract Doc Link 10995884 Disease Relevance 0.50 Pain Relevance 0.08
The nicotinic acetyl-choline receptor (AChR), ryanodine receptor (RyR), omega-conotoxin receptor (P/Q-type voltage-gated calcium channel), dihydropyridine receptor (L-type voltage gated calcium channel), and androgen receptor have been found to be affected by autoantibodies and/or genetic anomalies.
Regulation (affected) of androgen receptor associated with calcium channel and conotoxin
6) Confidence 0.01 Published 2000 Journal Rinsho Byori Section Abstract Doc Link 10892286 Disease Relevance 1.13 Pain Relevance 0.29

General Comments

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