INT68557

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Context Info
Confidence 0.02
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZNF697, PTGS1) aging (PTGS1) DNA binding (ZNF697)
lipid binding (PTGS1) oxidoreductase activity (PTGS1) plasma membrane (PTGS1)
ZNF697 (Homo sapiens)
PTGS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
diclofenac 2 98.36 Very High Very High Very High
cINOD 2 81.20 Quite High
dexamethasone 1 74.24 Quite High
cytokine 4 70.08 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Osteogenic Sarcomas 8 92.08 High High
INFLAMMATION 1 80.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DuP-697 and sulindac sulfide were also potent inhibitors of PGHS-2 but both compounds inhibited cellular PGHS-1 activity at higher doses (IC50 = 0.2-0.4 microM).
DuP-697 Negative_regulation (inhibited) of PGHS-1
1) Confidence 0.02 Published 1997 Journal Inflamm. Res. Section Abstract Doc Link 9085144 Disease Relevance 0.59 Pain Relevance 0.33

General Comments

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