INT68564

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Context Info
Confidence 0.32
First Reported 1997
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 6.75
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Fap) extracellular space (Fap)
Anatomy Link Frequency
pancreas 1
acinar cell 1
Fap (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 3 92.60 High High
Angina 1 90.76 High High
imagery 16 85.36 High High
carpal tunnel syndrome 1 74.48 Quite High
Pain 4 71.68 Quite High
Spinal cord 1 67.04 Quite High
Central nervous system 12 66.00 Quite High
cva 2 65.12 Quite High
abdominal pain 6 50.00 Quite Low
withdrawal 1 26.40 Quite Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 231 100.00 Very High Very High Very High
Pancreatic Cancer 19 100.00 Very High Very High Very High
Adrenal Cancer 8 99.92 Very High Very High Very High
Adenoma 20 99.48 Very High Very High Very High
Desmoid Disease 60 99.16 Very High Very High Very High
Recurrence 9 98.92 Very High Very High Very High
Cancer 71 98.84 Very High Very High Very High
Thyroid Neoplasm 26 98.30 Very High Very High Very High
Pancreatic Cyst 4 94.96 High High
Fibroma 7 92.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We report a patient with FAP and intra-abdominal desmoid tumors that regressed markedly after prednisolone therapy.
FAP Binding (patient) of associated with cancer, desmoid disease and familial adenomatous polyposis
1) Confidence 0.32 Published 1997 Journal J. Gastroenterol. Section Abstract Doc Link 9085178 Disease Relevance 1.49 Pain Relevance 0.24
The patient therefore underwent surgical resection of the distal pancreas, which included the lesion, because of the known association of pancreatic cancer with FAP.
FAP Binding (association) of in pancreas associated with familial adenomatous polyposis and pancreatic cancer
2) Confidence 0.31 Published 2005 Journal Fam. Cancer Section Abstract Doc Link 15951964 Disease Relevance 1.50 Pain Relevance 0.09
Logistic regression analysis indicated that FAP was associated with a significantly increased risk of BSD symptoms [Odds ratio (OR): 4.17] after controlling for psychopathology.
FAP Binding (associated) of
3) Confidence 0.24 Published 2007 Journal J Pediatr Psychol Section Body Doc Link 17627965 Disease Relevance 0.07 Pain Relevance 0
Parent and child reports of sleep problems were compared across groups and the association of FAP to behavioral sleep problems was assessed controlling for psychopathology.
FAP Binding (association) of
4) Confidence 0.24 Published 2007 Journal J Pediatr Psychol Section Body Doc Link 17627965 Disease Relevance 0.09 Pain Relevance 0
Two cases of intraductal papillary-mucinous neoplasm,52,53 one cystic and papillary carcinoma,54 one acinar cell carcinoma55 and two islet cell tumors56,57 have been reported in association with FAP.
FAP Binding (association) of in acinar cell associated with thyroid neoplasm, cancer and familial adenomatous polyposis
5) Confidence 0.15 Published 2008 Journal Ann Surg Oncol Section Body Doc Link PMC2518080 Disease Relevance 2.33 Pain Relevance 0.14
The latter was associated with multiple and bilateral adenomas.68 Adrenal carcinomas in association with FAP are very rare and only six have been described.69,70,72,78–80

Clinical Findings

FAP Binding (association) of associated with adenoma, familial adenomatous polyposis and adrenal cancer
6) Confidence 0.15 Published 2008 Journal Ann Surg Oncol Section Body Doc Link PMC2518080 Disease Relevance 0.92 Pain Relevance 0.07
Non-Val30Met TTR type FAP is being increasingly recognized; a total of 21 TTR gene mutations related to the development of non-Val30Met type FAP have been identified among Japanese.
FAP Binding (recognized) of
7) Confidence 0.05 Published 2003 Journal Amyloid Section Abstract Doc Link 14640041 Disease Relevance 0.28 Pain Relevance 0.11

General Comments

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