INT68582

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Context Info
Confidence 0.73
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.02
Pain Relevance 1.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (CNTF) cytosol (CNTF) signal transduction (CNTF)
extracellular space (CNTF) growth (CNTF) nucleus (CNTF)
Anatomy Link Frequency
brain 1
peripheral nerve 1
brachial plexus 1
RBMC 1
CNTF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 23 100.00 Very High Very High Very High
Peripheral nerve injury 6 97.64 Very High Very High Very High
Hyperalgesia 3 96.60 Very High Very High Very High
Thalamus 1 96.20 Very High Very High Very High
Peripheral nervous system 1 93.92 High High
Central nervous system 4 91.88 High High
Neurotransmitter 1 89.76 High High
Inflammation 1 74.60 Quite High
Spinal cord 1 49.44 Quite Low
Lasting pain 2 48.40 Quite Low
Disease Link Frequency Relevance Heat
Nervous System Injury 8 97.20 Very High Very High Very High
Hyperalgesia 3 96.60 Very High Very High Very High
Injury 54 84.08 Quite High
Cicatrix 6 79.92 Quite High
Weight Loss 1 78.64 Quite High
Neuroma 4 74.64 Quite High
Optic Nerve Injuries 11 74.60 Quite High
INFLAMMATION 1 74.60 Quite High
Disease 1 65.96 Quite High
Motor Neuron Diseases 1 64.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rat brain mast cells (RBMC) released histamine in a concentration dependent manner in response to NTFs, with a rank order of BDNF > CNTF > NGF; in contrast RPMC were refractory to the effects of BDNF and CNTF.
Localization (released) of CNTF in RBMC associated with nerve growth factor
1) Confidence 0.73 Published 1996 Journal Neurotoxicology Section Abstract Doc Link 9086508 Disease Relevance 0.42 Pain Relevance 0.39
It has been shown that OECs secrete neurotrophic factors (NTFs), including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3/4 (NT-3/4), and ciliary neurotrophic factor (CNTF).
Localization (secrete) of CNTF in brain associated with nerve growth factor
2) Confidence 0.68 Published 2010 Journal Molecular Vision Section Body Doc Link PMC3013062 Disease Relevance 0.42 Pain Relevance 0.17
In this first study of injured human nerves and sensory ganglia, we quantified and localized endogenous NGF and CNTF in 59 neonate and adult patients with brachial plexus and peripheral nerve injury.
Localization (localized) of CNTF in brachial plexus associated with nervous system injury, nerve growth factor and peripheral nerve injury
3) Confidence 0.60 Published 1997 Journal Neuroreport Section Abstract Doc Link 9223080 Disease Relevance 0.59 Pain Relevance 0.56
In this first study of injured human nerves and sensory ganglia, we quantified and localized endogenous NGF and CNTF in 59 neonate and adult patients with brachial plexus and peripheral nerve injury.
Localization (localized) of CNTF in peripheral nerve associated with nervous system injury, nerve growth factor and peripheral nerve injury
4) Confidence 0.21 Published 1997 Journal Neuroreport Section Abstract Doc Link 9223080 Disease Relevance 0.59 Pain Relevance 0.56

General Comments

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