INT68684
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Since relaxin regulates the expression of MMPs and VEGF in the endometrium, we tested the hypothesis that relaxin plays a role in endometriosis by comparing the expression of relaxin mRNA and its LGR7 (RXFP1) receptor mRNA in normal human endometrium to those in samples from patients with endometriosis. | |||||||||||||||
| |||||||||||||||
|
Herein, we examined the expression of VEGF in synovial fibroblasts from temporomandibular joint (TMJ) under hypoxia and investigated the regulation of hypoxia-inducible factor-1alpha (HIF-1alpha) involved in the expression of VEGF. | |||||||||||||||
| |||||||||||||||
|
HIF-1alpha, which is clearly activated in response to hypoxia, may control the expression of VEGF in synovial fibroblasts from TMJ.
| |||||||||||||||
| |||||||||||||||
|
INTRODUCTION: Enhanced expression of vascular endothelial growth factor (VEGF) has been described in patients with internal derangement (ID). | |||||||||||||||
| |||||||||||||||
|
INTRODUCTION: Enhanced expression of vascular endothelial growth factor (VEGF) has been described in patients with internal derangement (ID). | |||||||||||||||
| |||||||||||||||
|
CONCLUSIONS: Hypoxia may mainly induce the expression of VEGF121 and VEGF165 in synovial fibroblasts to promote inflamed angiogenesis of TMJ. | |||||||||||||||
| |||||||||||||||
|
Herein, we examined the expression of VEGF in synovial fibroblasts from temporomandibular joint (TMJ) under hypoxia and investigated the regulation of hypoxia-inducible factor-1alpha (HIF-1alpha) involved in the expression of VEGF. | |||||||||||||||
| |||||||||||||||
|
VEGF expression in the stromal cells in healthy pulps ranged from 20 to 100% (with a mean of 68.82), and in irreversible pulpitis ranged from 0 to 100% (with a mean of 62.35%); this difference was statistically significant (p = 0.05). | |||||||||||||||
| |||||||||||||||
|
Vascular endothelial growth factor (VEGF) expression in healthy and inflamed human dental pulps. | |||||||||||||||
| |||||||||||||||
|
Our immunohistochemical data show that the expression of VEGF was strongly positive in the inflammatory infiltrate in irreversible pulpitis. | |||||||||||||||
| |||||||||||||||
|
Vascular endothelial growth factor (VEGF) expression in healthy and inflamed human dental pulps. | |||||||||||||||
| |||||||||||||||
|
VEGF has been found to be expressed in several different types of tumors, and it may contribute to the progression of malignant tumors. | |||||||||||||||
| |||||||||||||||
|
Expression of vascular endothelial growth factor in human dysfunctional temporomandibular joint discs. | |||||||||||||||
| |||||||||||||||
|
The purpose here was to investigate, in human TMJ discs, the expression of vascular endothelial growth factor (VEGF), a multifunctional cytokine that contributes to angiogenesis. | |||||||||||||||
| |||||||||||||||
|
Therefore VEGF expression by disc chondrocyte-like cells might reflect the action of the cytokine as an inducer of angiogenesis and as an autocrine signal for cells of the chondrogenic lineage. | |||||||||||||||
| |||||||||||||||
|
In disc specimens from internal derangement of the TMJ with significant tissue degeneration/regeneration, VEGF was consistently expressed. | |||||||||||||||
| |||||||||||||||
|
The purpose here was to investigate, in human TMJ discs, the expression of vascular endothelial growth factor (VEGF), a multifunctional cytokine that contributes to angiogenesis. | |||||||||||||||
| |||||||||||||||
|
VEGF has more recently, also been shown to be expressed in articular cartilage chondrocytes in human osteoarthritic and rheumatoarthritic joints but not healthy adult joints. | |||||||||||||||
| |||||||||||||||
|
Immunohistochemical staining was employed to determine the microvessel density (MVD) and vascular endothelial growth factor (VEGF) expression in tumor tissues. | |||||||||||||||
| |||||||||||||||
|
Immunohistochemical staining was employed to determine the microvessel density (MVD) and vascular endothelial growth factor (VEGF) expression in tumor tissues. | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.