INT68693

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Context Info
Confidence 0.45
First Reported 1997
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.72
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (HTT) endoplasmic reticulum (HTT) protein complex (HTT)
cytoplasm (HTT) cytosol (HTT) cell death (HTT)
Anatomy Link Frequency
neurons 2
dermis 2
HTT (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 1 61.44 Quite High
imagery 18 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
Pain 11 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cryotherapy 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Wound Healing 37 98.92 Very High Very High Very High
Blister 65 98.04 Very High Very High Very High
Disease 9 97.60 Very High Very High Very High
Repression 6 82.92 Quite High
Injury 214 67.44 Quite High
Tremor 4 50.00 Quite Low
Ataxia 3 50.00 Quite Low
Burns 82 35.04 Quite Low
Death 11 21.76 Low Low
Bacteremia 1 10.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Combined techniques for NADPH-diaphorase enzyme histochemistry and huntingtin immunocytochemistry, as well as double immunofluorescence for either nitric oxide synthase or calbindin D28k in comparison with huntingtin expression, revealed a striking correspondence between calbindin D28k and huntingtin immunoreactivities, with little or no colocalization between NADPH-diaphorase or nitric oxide synthase neurons and huntingtin expression.
Neg (little) Regulation (colocalization) of Gene_expression (expression) of huntingtin in neurons
1) Confidence 0.45 Published 1997 Journal J. Neurosci. Section Abstract Doc Link 9096140 Disease Relevance 0.09 Pain Relevance 0.06
Moreover, global HDAC inhibition or selective siRNA knockdown of HDAC3 or 6 does not alter expression of uas-HTT transgenes in a separate Drosophila model of polyglutamine disease [34].
Neg (not) Regulation (alter) of Gene_expression (expression) of HTT associated with disease
2) Confidence 0.26 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC3000359 Disease Relevance 0.28 Pain Relevance 0
Beyond the BMZ, dermal collagen itself is affected by HD exposure and can itself impede the wound healing process.97,106,197 Brown and Rice197 reported coagulation and hypereosinophilia of the papillary dermis in Yucatan minipig skin 12 to 24 hours following saturated HD vapor exposure, with the deeper reticular dermis unaffected.
Regulation (affected) of Gene_expression (exposure) of HD in dermis associated with wound healing
3) Confidence 0.05 Published 2005 Journal Journal of Burns and Wounds Section Body Doc Link PMC1501116 Disease Relevance 0.35 Pain Relevance 0

General Comments

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