INT6884

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Context Info
Confidence 0.42
First Reported 1987
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 20
Total Number 21
Disease Relevance 13.18
Pain Relevance 7.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
foot 2
blood 1
synapse 1
pr (Mus musculus)
Pain Link Frequency Relevance Heat
Oxycodone 178 100.00 Very High Very High Very High
narcan 142 100.00 Very High Very High Very High
headache 15 99.84 Very High Very High Very High
Clonidine 12 99.72 Very High Very High Very High
Pain 107 99.64 Very High Very High Very High
Pain score 29 99.16 Very High Very High Very High
Serotonin 14 96.72 Very High Very High Very High
positron emission tomography 101 96.44 Very High Very High Very High
Regional anesthesia 3 95.36 Very High Very High Very High
Versed 5 95.28 Very High Very High Very High
Disease Link Frequency Relevance Heat
Uterine Fibroids 10 99.90 Very High Very High Very High
Cancer 344 99.84 Very High Very High Very High
Headache 14 99.84 Very High Very High Very High
Diabetes Mellitus 169 99.64 Very High Very High Very High
Pain 156 99.64 Very High Very High Very High
Metastasis 120 99.52 Very High Very High Very High
Disease 177 97.48 Very High Very High Very High
Constipation 84 96.24 Very High Very High Very High
Malignant Neoplastic Disease 24 95.96 Very High Very High Very High
Sleep Disorders 2 94.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors also recorded patients' blood pressure (BP) and pulse rate (PR).
Negative_regulation (recorded) of PR in blood
1) Confidence 0.42 Published 2009 Journal J Am Dent Assoc Section Body Doc Link 19955069 Disease Relevance 0 Pain Relevance 0
Previous case reports have indicated the effect of physostigmine in reversing PR following various bzdp's.
Negative_regulation (reversing) of PR
2) Confidence 0.18 Published 1987 Journal Anaesthesist Section Abstract Doc Link 3592209 Disease Relevance 0.28 Pain Relevance 0.45
PR was defined as decreased to mild pain, with a pain score of no more than 4 on a 0-10 VAS.
Negative_regulation (decreased) of PR associated with pain and pain score
3) Confidence 0.08 Published 2006 Journal Oncol. Rep. Section Abstract Doc Link 17016596 Disease Relevance 1.10 Pain Relevance 1.50
In clinical trials, PR is typically defined as a reduction in headache pain severity from moderate/severe to mild/none (10).
Negative_regulation (reduction) of PR associated with pain and headache
4) Confidence 0.08 Published 2007 Journal International Journal of Clinical Practice Section Body Doc Link PMC1974799 Disease Relevance 0.61 Pain Relevance 0.75
PR was defined as a reduction of each lesion by at least 50%.
Negative_regulation (reduction) of PR
5) Confidence 0.05 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1579231 Disease Relevance 0.73 Pain Relevance 0.03
In this paper, we present our study on the correlation of TPD with other measures such as loss of protective sensation, hardness of the sole and PR in foot areas of DM patients.
Negative_regulation (loss) of PR in foot associated with diabetes mellitus
6) Confidence 0.04 Published 2008 Journal International Journal of Diabetes in Developing Countries Section Body Doc Link PMC2772015 Disease Relevance 0.47 Pain Relevance 0
Studies were performed to determine (1) whether blocking nuclear PR would block P-induced prolactin secretion and conversely; (2) whether increasing serotonin concentrations in the synapse would augment P-induced prolactin secretion.
Spec (whether) Negative_regulation (blocking) of PR in synapse associated with serotonin
7) Confidence 0.04 Published 1997 Journal Neuroendocrinology Section Abstract Doc Link 9158065 Disease Relevance 0 Pain Relevance 0.26
To block nuclear PR and not membrane PR, RU 486 (2 mg/kg, i.m.) or ethanol (control) was administered with the P injection.
Negative_regulation (block) of PR
8) Confidence 0.03 Published 1997 Journal Neuroendocrinology Section Abstract Doc Link 9158065 Disease Relevance 0 Pain Relevance 0.44
We have evaluated the correlation of different measures of sensory loss such as TPD, shore values and PR in both foot areas of DM subjects.
Negative_regulation (loss) of PR in foot associated with diabetes mellitus
9) Confidence 0.03 Published 2008 Journal International Journal of Diabetes in Developing Countries Section Body Doc Link PMC2772015 Disease Relevance 0.63 Pain Relevance 0.09
We measured the loss of protective sensation, hardness of the sole, PR and (14 diabetic subject, 4 normal subjects).
Negative_regulation (loss) of PR associated with diabetes mellitus
10) Confidence 0.03 Published 2008 Journal International Journal of Diabetes in Developing Countries Section Body Doc Link PMC2772015 Disease Relevance 0.36 Pain Relevance 0
The decrease in PR was correlated with neither delta p-GH (N: r = 0.082, DM-NR: r = -0.400, DM-HR: r = 0.242) or integral of GH (N: r = 0.191, DM-NR: r = 0.382, DM-HR: r = 0.162).
Negative_regulation (decrease) of PR associated with diabetes mellitus
11) Confidence 0.03 Published 1992 Journal Nippon Naibunpi Gakkai Zasshi Section Abstract Doc Link 1334889 Disease Relevance 1.42 Pain Relevance 0.47
Type II DM were classified as DM with hyper-response (DM-HR, n = 12) when their PR decreased after clonidine more than that of N, and if not, they were classified as DM with normal response (DM-NR, n = 23).
Negative_regulation (decreased) of PR associated with diabetes mellitus and clonidine
12) Confidence 0.03 Published 1992 Journal Nippon Naibunpi Gakkai Zasshi Section Abstract Doc Link 1334889 Disease Relevance 1.31 Pain Relevance 0.56
In 19 out of 36 responders, the achieved PR was only based on a decrease in tumor attenuation ?
Negative_regulation (decrease) of PR associated with cancer
13) Confidence 0.02 Published 2010 Journal Target Oncol Section Body Doc Link PMC2929340 Disease Relevance 0.98 Pain Relevance 0.06
According to Choi et al. [33, 34], a PR is defined as a ?
Negative_regulation (defined) of PR
14) Confidence 0.02 Published 2010 Journal Target Oncol Section Body Doc Link PMC2929340 Disease Relevance 1.32 Pain Relevance 0.10
Following this, BFI scores decreased at a similar rate to those in patients who had received oxycodone PR/naloxone PR in the double-blind study.
Negative_regulation (received) of PR associated with oxycodone and narcan
15) Confidence 0.02 Published 2010 Journal International Journal of Clinical Practice Section Body Doc Link PMC2948431 Disease Relevance 0.31 Pain Relevance 1.56
The tapes are selected so that: (1) approximately equal numbers come from each therapist, (2) approximately equal numbers of PR and SL are represented and (3) all treatment sessions are represented, but are otherwise selected at random.
Negative_regulation (numbers) of PR
16) Confidence 0.02 Published 2006 Journal BMC Med Section Body Doc Link PMC1456982 Disease Relevance 0 Pain Relevance 0
RESULTS: Twenty-three of 38 patients (60.5%) receiving this combination regimen had partial responses [PR, >/=50% prostate-specific antigen (PSA) decline], 9 (21.1%) had stable disease, and 7 (18.4%) had progressive disease.
Negative_regulation (decline) of PR
17) Confidence 0.02 Published 2004 Journal Clin. Cancer Res. Section Body Doc Link 15240528 Disease Relevance 0 Pain Relevance 0
Following this, BFI scores decreased at a similar rate to those in patients who had received oxycodone PR/naloxone PR in the double-blind study.
Negative_regulation (received) of PR associated with oxycodone and narcan
18) Confidence 0.02 Published 2010 Journal International Journal of Clinical Practice Section Body Doc Link PMC2948431 Disease Relevance 0.31 Pain Relevance 1.56
PR is defined as a decrease of ?
Negative_regulation (decrease) of PR
19) Confidence 0.02 Published 2010 Journal Journal of Cancer Section Body Doc Link PMC2938069 Disease Relevance 1.15 Pain Relevance 0.08
A PR was defined as an at least 30% decrease in the sum of the longest diameters of the target lesions for more than 4 weeks without new area of malignant disease.
Negative_regulation (decrease) of PR associated with malignant neoplastic disease and disease
20) Confidence 0.01 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2954881 Disease Relevance 1.33 Pain Relevance 0

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