INT68850

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Context Info
Confidence 0.19
First Reported 1997
Last Reported 2004
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NQO1) small molecule metabolic process (NQO1) oxidoreductase activity (NQO1)
cellular nitrogen compound metabolic process (NQO1) cytoplasm (NQO1)
Anatomy Link Frequency
spinal 1
NQO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal dorsal horn 7 98.92 Very High Very High Very High
qutenza 2 98.40 Very High Very High Very High
Hyperalgesia 1 54.96 Quite High
central sensitization 1 54.28 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 2 75.00 Quite High
Hyperalgesia 1 54.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibitors of glucose uptake and glycolysis, the ubiquinone redox cycle inhibitors, capsaicin and resiniferatoxin, the flavin centre inhibitor, diphenyleneiodonium, and the NQO1 inhibitor, dicoumarol, all inhibited oxygen consumption by HL60rho(0) cells.
Negative_regulation (inhibitor) of NQO1 associated with qutenza
1) Confidence 0.19 Published 2004 Journal Biochim. Biophys. Acta Section Abstract Doc Link 15178469 Disease Relevance 0.14 Pain Relevance 0.10
Localization of NADPH-diaphorase containing neurons in the spinal dorsal horn and spinal sensory ganglia of the turtle Chrysemys d'orbigny.
Negative_regulation (Localization) of NADPH-diaphorase in spinal associated with spinal dorsal horn
2) Confidence 0.09 Published 1997 Journal Exp Brain Res Section Title Doc Link 9108212 Disease Relevance 0.05 Pain Relevance 0.33

General Comments

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