INT6916

Context Info Confidence 0.01 First Reported 1992 Last Reported 1992 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.40

peptidase activity (Phex) Golgi apparatus (Phex) endoplasmic reticulum (Phex)

Anatomy Link Frequency face 1 Phex (Mus musculus)

Pain Link Frequency Relevance Heat sodium channel 4 98.92 tetrodotoxin 1 86.96 conotoxin 4 81.24

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the determined structure, important residues for the activity, Arg13, Lys16, Hyp(hydroxyproline)17, and Arg19, are clustered on one side of the molecule, an observation which suggests that this face of the molecule associates with the receptor site of sodium channels.

Hyp Binding (associates) of in face associated with sodium channel

1) Confidence 0.01 Published 1992 Journal Biochemistry Section Abstract Doc Link 1335283 Disease Relevance 0 Pain Relevance 0.40

General Comments

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