INT69282

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Context Info
Confidence 0.15
First Reported 1997
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.43
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PHEX) protein modification process (PHEX) Golgi apparatus (PHEX)
endoplasmic reticulum (PHEX) plasma membrane (PHEX) cell-cell signaling (PHEX)
Anatomy Link Frequency
plasma 1
erythrocyte 1
Hyp12 1
PHEX (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 23 94.88 High High
ischemia 2 89.00 High High
medulla 3 88.64 High High
Inflammation 5 85.40 High High
Neuropeptide 1 83.28 Quite High
Potency 2 79.52 Quite High
Enkephalin 1 79.20 Quite High
Pain 2 68.92 Quite High
Action potential 7 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rickets 1 99.40 Very High Very High Very High
Adhesions 45 95.32 Very High Very High Very High
Cv Unclassified Under Development 2 89.00 High High
Motor Neuron Diseases 3 88.04 High High
Guillain-barre Syndrome 5 87.12 High High
Chronic Progressive External Ophthalmoplegia 1 84.60 Quite High
Mitochondrial Disorders 1 82.72 Quite High
Poisoning 1 81.72 Quite High
Gastroenteritis 2 80.52 Quite High
Syndrome 3 80.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rapid, temporary improvement may be achieved for myasthenic crises and exacerbations with plasma exchange (PEX) or intravenous immunoglobulin (IVIg).
PEX Binding (exacerbations) of in plasma
1) Confidence 0.15 Published 2007 Journal Orphanet J Rare Dis Section Abstract Doc Link PMC2211463 Disease Relevance 1.01 Pain Relevance 0.18
The role of HYP in GpVI-dependent binding was investigated by modifying III-30 with HYP?
HYP Binding (modifying) of
2) Confidence 0.06 Published 2008 Journal Blood Section Body Doc Link PMC2602586 Disease Relevance 0.18 Pain Relevance 0
Two other mammalian gene products exhibit strong homology with NEP: the erythrocyte cell-surface antigen, KELL; and the putative product of the PEX gene, which has been associated with X-linked hypophosphatemic rickets.
PEX gene Binding (associated) of in erythrocyte associated with rickets
3) Confidence 0.05 Published 1997 Journal FASEB J. Section Abstract Doc Link 9141502 Disease Relevance 0.18 Pain Relevance 0.12
In particular, noncovalent interactions between Val3 and Hyp12 are likely to be involved in maintaining a stable conformation.
Hyp12 Binding (interactions) of in Hyp12
4) Confidence 0.04 Published 2005 Journal Biopolymers Section Abstract Doc Link 15931669 Disease Relevance 0.07 Pain Relevance 0.11

General Comments

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