INT69340

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Context Info
Confidence 0.06
First Reported 1997
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.04
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ngf) extracellular space (Ngf) aging (Ngf)
extracellular region (Ngf) molecular_function (Ngf)
Anatomy Link Frequency
nerve 1
Igh-6 (Rattus norvegicus)
Ngf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 18 100.00 Very High Very High Very High
Neuropathic pain 3 95.80 Very High Very High Very High
Sciatic nerve 2 94.08 High High
Inflammation 10 92.96 High High
Bioavailability 1 92.48 High High
Peripheral nerve injury 1 28.40 Quite Low
qutenza 2 25.00 Low Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 3 95.80 Very High Very High Very High
Neuroma 4 93.40 High High
INFLAMMATION 10 92.96 High High
Cystitis 2 81.76 Quite High
Sensation Disorders 2 67.64 Quite High
Nervous System Injury 1 27.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study we attempted to antagonize NGF by using trkA-IgG, an inhibitor of NGF, consisting of the NGF receptor linked to an immunoglobulin.
immunoglobulin Binding (linked) of NGF associated with nerve growth factor
1) Confidence 0.06 Published 2001 Journal J Hand Surg Am Section Abstract Doc Link 11466637 Disease Relevance 0.34 Pain Relevance 0.53
A synthetic fusion protein was used, consisting of the extracelluar domain of the high-affinity nerve growth factor receptor, trkA, coupled to the Fc portion of an immunoglobulin.
immunoglobulin Binding (coupled) of nerve growth factor in nerve associated with nerve growth factor
2) Confidence 0.01 Published 1997 Journal Neuroscience Section Abstract Doc Link 9145801 Disease Relevance 0.70 Pain Relevance 0.53

General Comments

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