INT69393

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Context Info
Confidence 0.45
First Reported 1997
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.80
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CNTN2) plasma membrane (CNTN2)
Anatomy Link Frequency
glial cells 2
CNTN2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 99.86 Very High Very High Very High
addiction 6 99.30 Very High Very High Very High
Neurotransmitter 2 60.00 Quite High
Opioid 2 58.24 Quite High
Enkephalin 4 57.80 Quite High
cytokine 8 5.00 Very Low Very Low Very Low
iatrogenic 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 1 99.86 Very High Very High Very High
Sprains And Strains 5 99.12 Very High Very High Very High
Leukemia 17 98.80 Very High Very High Very High
Nicotine Addiction 4 98.76 Very High Very High Very High
Contagious Ecthyma 5 80.56 Quite High
Neurological Disease 2 50.68 Quite High
Enzootic Bovine Leukosis 13 50.00 Quite Low
Htlv Types I And Ii 8 49.40 Quite Low
Lymphocytosis 33 5.00 Very Low Very Low Very Low
Infection 26 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the contrary, if smokers are trapped into addiction and can't stop without pain, then tax increase is imposing too much strain on them, for no result.
Positive_regulation (increase) of tax associated with pain, addiction, nicotine addiction and sprains and strains
1) Confidence 0.45 Published 2004 Journal Med Sci (Paris) Section Abstract Doc Link 15361350 Disease Relevance 0.52 Pain Relevance 0.33
The tax1 induced c-Fos protein levels and the concurrently increased association of c-Fos/c-Jun transcription factors at the AP-1 site imply a strong functional significance in the activation of proenkephalin gene expression in tax1 expressing glial cells.
Positive_regulation (activation) of tax1 in glial cells
2) Confidence 0.41 Published 1997 Journal J. Neurovirol. Section Abstract Doc Link 9147818 Disease Relevance 0 Pain Relevance 0.03
The c-Fos protein expression significantly increased in the tax1 expressing glial cells.
Positive_regulation (increased) of tax1 in glial cells
3) Confidence 0.41 Published 1997 Journal J. Neurovirol. Section Abstract Doc Link 9147818 Disease Relevance 0.05 Pain Relevance 0.15
The Tax transactivator
Positive_regulation (transactivator) of Tax
4) Confidence 0.17 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0.23 Pain Relevance 0

General Comments

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