INT69421

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Context Info
Confidence 0.23
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.56
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ACAT1) small molecule metabolic process (ACAT1) enzyme binding (ACAT1)
cellular nitrogen compound metabolic process (ACAT1)
Anatomy Link Frequency
heart 1
MAT-LyLu 1
ACAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tetrodotoxin 5 99.48 Very High Very High Very High
noradrenaline 2 98.30 Very High Very High Very High
narcan 2 97.00 Very High Very High Very High
Catecholamine 2 92.88 High High
Dynorphin 1 92.00 High High
Bile 2 90.76 High High
Endogenous opioid 1 81.84 Quite High
imagery 7 81.56 Quite High
Opioid 1 75.00 Quite High
Inflammation 54 65.28 Quite High
Disease Link Frequency Relevance Heat
Prostate Cancer 3 99.80 Very High Very High Very High
Fever 27 93.20 High High
Infection 12 89.32 High High
Natriuresis 1 86.48 High High
Leptospirosis 86 79.36 Quite High
Stress 4 75.00 Quite High
Toxicity 1 70.32 Quite High
Heart Disease 3 67.60 Quite High
INFLAMMATION 68 65.28 Quite High
Hypertension 3 61.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment with naloxone hydrochloride enhanced (p < 0.01) SBP, heart rate, noradrenaline, cortisol, and endothelin-1 levels, and reduced (p < 0.01) ANF in low responders in response to MAT, whereas it decreased (p < 0.01) hemodynamic parameters, noradrenaline, and endothelin-1 in high responders.
Positive_regulation (response) of MAT in heart associated with noradrenaline and narcan
1) Confidence 0.23 Published 1997 Journal Peptides Section Abstract Doc Link 9149287 Disease Relevance 0.16 Pain Relevance 0.44
Tetrodotoxin suppresses morphological enhancement of the metastatic MAT-LyLu rat prostate cancer cell line.
Positive_regulation (enhancement) of MAT-LyLu in MAT-LyLu associated with tetrodotoxin and prostate cancer
2) Confidence 0.14 Published 1999 Journal Cell Tissue Res. Section Title Doc Link 10022970 Disease Relevance 0.26 Pain Relevance 0.42
The balanced cine SSFP sequence is known to generate T2/T1-weighting.
Positive_regulation (generate) of T2
3) Confidence 0.03 Published 2010 Journal J Cardiovasc Magn Reson Section Body Doc Link PMC2885384 Disease Relevance 0.16 Pain Relevance 0.10
Both patients initially had negative MAT and IgM results in their acute serum sample.
Positive_regulation (results) of MAT
4) Confidence 0.01 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2271056 Disease Relevance 0.50 Pain Relevance 0
Synthesis begins when acetyl-CoA is derived from an oxidation reaction in the mitochondria and is transported to the cytoplasm
Positive_regulation (derived) of acetyl-CoA
5) Confidence 0.01 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.47 Pain Relevance 0.12

General Comments

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