INT69513

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Context Info
Confidence 0.60
First Reported 1997
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.04
Pain Relevance 1.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PSMA5) nucleoplasm (PSMA5) peptidase activity (PSMA5)
small molecule metabolic process (PSMA5) nucleolus (PSMA5) nucleus (PSMA5)
Anatomy Link Frequency
chondrocytes 1
frontal cortex 1
PSMA5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 5 100.00 Very High Very High Very High
mu opioid receptor 4 100.00 Very High Very High Very High
opiate 6 98.36 Very High Very High Very High
opioid receptor 2 96.76 Very High Very High Very High
addiction 2 94.16 High High
cINOD 8 93.84 High High
methadone 1 88.00 High High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 2 99.32 Very High Very High Very High
Apoptosis 10 98.88 Very High Very High Very High
Opiate Addiction 2 94.44 High High
INFLAMMATION 2 93.44 High High
Overdose 1 87.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulation of immunolabelled mu-opioid receptors and protein kinase C-alpha and zeta isoforms in the frontal cortex of human opiate addicts.
Regulation (Regulation) of zeta in frontal cortex associated with kinase c, mu opioid receptor, urological neuroanatomy and opiate
1) Confidence 0.60 Published 1997 Journal Neurosci. Lett. Section Title Doc Link 9153634 Disease Relevance 0.43 Pain Relevance 0.99
Nitric oxide (NO) causes apoptosis and dedifferentiation of articular chondrocytes by the modulation of extracellular signal-regulated kinase (ERK), p38 kinase, and protein kinase C (PKC) alpha and -zeta.
Regulation (modulation) of zeta in chondrocytes associated with kinase c and apoptosis
2) Confidence 0.26 Published 2003 Journal J. Biol. Chem. Section Abstract Doc Link 12588866 Disease Relevance 0.61 Pain Relevance 0.44

General Comments

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