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Context Info
Confidence 0.64
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (YY1) chromosome organization (YY1) RNA binding (YY1)
plasma membrane (YY1) nucleus (YY1) intracellular (YY1)
Anatomy Link Frequency
reticulum 1
YY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 100.00 Very High Very High Very High
Somatostatin 1 99.90 Very High Very High Very High
Neurotransmitter 1 98.38 Very High Very High Very High
fibrosis 5 93.96 High High
Bioavailability 2 84.16 Quite High
potassium channel 1 75.00 Quite High
action potential duration 1 61.08 Quite High
Analgesic 1 60.16 Quite High
Disease Link Frequency Relevance Heat
Cystic Fibrosis 5 93.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GIRKs, as heteromultimers, compose the G protein-gated Kir (KG) channels, which are regulated by a variety of Gi/Go-coupled inhibitory neurotransmitter receptors such as m2-mus-carinic, serotonergic (5HT1A), GABAB, somatostatin and opioid (mu, delta, kappa) receptors.
Protein_catabolism (opioid) of delta associated with neurotransmitter, somatostatin and opioid
1) Confidence 0.64 Published 1997 Journal Jpn. J. Physiol. Section Abstract Doc Link 9159640 Disease Relevance 0 Pain Relevance 0.27
The most common mutation Delta Phe508 leads to protein misfolding, retention by the endoplasmic reticulum, and degradation.
Protein_catabolism (degradation) of Delta in reticulum
2) Confidence 0.08 Published 2010 Journal Mol. Pharmacol. Section Abstract Doc Link 20200141 Disease Relevance 0.35 Pain Relevance 0.31

General Comments

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