INT69709

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Context Info
Confidence 0.36
First Reported 1997
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.22
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (NPL, POMC) small molecule metabolic process (POMC) lyase activity (NPL)
carbohydrate metabolic process (NPL) cell-cell signaling (POMC) extracellular space (POMC)
NPL (Homo sapiens)
POMC (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 18 100.00 Very High Very High Very High
fluoxetine 7 99.00 Very High Very High Very High
Opioid 3 81.68 Quite High
antagonist 1 72.16 Quite High
Serotonin 1 65.24 Quite High
Disease Link Frequency Relevance Heat
Frailty 10 98.84 Very High Very High Very High
Congenital Anomalies 2 86.64 High High
Muscle Weakness 1 72.68 Quite High
Hypopituitarism 1 71.52 Quite High
Stress 1 60.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fluoxetine produced a small but non-significant increase in Nal-stimulated ACTH and cortisol release in both morning and afternoon studies.
Nal Positive_regulation (stimulated) of Localization (release) of ACTH associated with narcan and fluoxetine
1) Confidence 0.36 Published 1997 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 9171947 Disease Relevance 0.06 Pain Relevance 1.12
Despite this DM patients have a relative resistance to APZ inhibition of Nal-induced ACTH/cortisol release.
Nal Positive_regulation (induced) of Localization (release) of ACTH associated with frailty and narcan
2) Confidence 0.36 Published 1998 Journal J. Neuroendocrinol. Section Abstract Doc Link 9663654 Disease Relevance 1.16 Pain Relevance 0.39

General Comments

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