INT69744

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Context Info
Confidence 0.65
First Reported 1997
Last Reported 2007
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.60
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDT1) nucleoplasm (CDT1) nucleus (CDT1)
DNA binding (CDT1)
Anatomy Link Frequency
spinal cord 1
CDT1 (Homo sapiens)
CDT1 - A40V (1)
Pain Link Frequency Relevance Heat
Hyperalgesia 3 99.46 Very High Very High Very High
Pain 2 98.94 Very High Very High Very High
Spinal cord 3 97.10 Very High Very High Very High
anesthesia 2 87.92 High High
Inflammation 1 83.32 Quite High
imagery 1 82.64 Quite High
Inflammatory response 1 82.32 Quite High
Central nervous system 1 79.32 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 3 99.46 Very High Very High Very High
Pain 1 98.94 Very High Very High Very High
Glioma 2 95.36 Very High Very High Very High
Congenital Anomalies 9 93.44 High High
Cleidocranial Dysplasia 6 91.08 High High
Pressure And Volume Under Development 1 90.24 High High
Syndrome 46 89.28 High High
INFLAMMATION 2 83.32 Quite High
Lissencephaly 2 31.20 Quite Low
Heart Rate Under Development 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we investigated whether COX-2 in spinal cord was similarly induced by carrageenan and whether the associated development of altered pain sensitivity, hyperalgesia was affected by the COX-2 selective inhibitor DuP 697.
Gene_expression (selective) of DuP in spinal cord associated with pain, hyperalgesia and spinal cord
1) Confidence 0.65 Published 1997 Journal Neuroreport Section Abstract Doc Link 9175123 Disease Relevance 0.62 Pain Relevance 0.58
FISH analyses confirmed the deletion of the 17p telomeric region (Fig. 3a) as well as the dup(17)(p11.2p12) (Fig. 3b).
Spec (analyses) Gene_expression (confirmed) of dup
2) Confidence 0.21 Published 2007 Journal Hum Genet Section Body Doc Link PMC1914245 Disease Relevance 0.25 Pain Relevance 0
We generated stable cell lines expressing enhanced yellow fluorescent protein (eYFP)-tagged human Cx43 constructs encoding wild-type and six eYFP-tagged mutant Cx43 mutants: Y17S, G21R, A40V, F52dup, L90V and I130T.
Gene_expression (expressing) of F52dup (A40V)
3) Confidence 0.01 Published 2006 Journal J. Cell. Sci. Section Abstract Doc Link 16418219 Disease Relevance 0.72 Pain Relevance 0.17

General Comments

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