INT69887

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Context Info
Confidence 0.49
First Reported 1997
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 2.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ngf, Calca) aging (Ngf, Calca) extracellular region (Ngf, Calca)
signal transduction (Ngf) nucleus (Calca) intracellular (Calca)
Anatomy Link Frequency
nerve 1
Ngf (Rattus norvegicus)
Calca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 109 100.00 Very High Very High Very High
Calcitonin gene-related peptide 102 100.00 Very High Very High Very High
c fibre 2 100.00 Very High Very High Very High
substance P 11 99.88 Very High Very High Very High
Neuropeptide 17 99.16 Very High Very High Very High
qutenza 52 88.96 High High
nociceptor 6 80.00 Quite High
Spinal cord 5 78.24 Quite High
Trigeminal ganglion neurons 1 50.00 Quite Low
trigeminal ganglion 59 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 9 99.40 Very High Very High Very High
Ganglion Cysts 73 50.00 Quite Low
Injury 23 5.00 Very Low Very Low Very Low
Hyperalgesia 7 5.00 Very Low Very Low Very Low
Headache 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Nervous System Injury 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the adult rat, nerve growth factor (NGF) upregulates the nociceptive peptide substance P (SP) and calcitonin gene-related peptide (CGRP) in neuronal cell bodies of C fibres but the effects of NGF on release of these neuropeptides from the central afferent terminals have not been reported.
NGF Regulation (effects) of calcitonin gene-related peptide in nerve associated with nociception, c fibre, nerve growth factor, neuropeptide, calcitonin gene-related peptide and substance p
1) Confidence 0.49 Published 1997 Journal Eur. J. Neurosci. Section Abstract Doc Link 9182964 Disease Relevance 0.10 Pain Relevance 1.05
On the other hand, normalization led to a further augmention in the effect of NGF on total CGRP content, up to a 5.8-fold increase.
NGF Regulation (effect) of CGRP associated with nerve growth factor and calcitonin gene-related peptide
2) Confidence 0.34 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0 Pain Relevance 1.13

General Comments

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