INT69989

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Context Info
Confidence 0.43
First Reported 1997
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.44
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Nefl) locomotion (Nefl) response to stress (Nefl)
Anatomy Link Frequency
frontal cortex 2
Nefl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
methadone 1 96.84 Very High Very High Very High
opiate 5 95.00 High High
Morphine 1 89.40 High High
induced neuropathy 1 72.80 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 99.12 Very High Very High Very High
Overdose 1 97.20 Very High Very High Very High
Drug Induced Neurotoxicity 2 84.12 Quite High
Neurodegenerative Disease 1 79.36 Quite High
Neuropathic Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Levels of immunoreactive NF-L proteins were markedly decreased (47%, n = 17) in the frontal cortex.
Negative_regulation (decreased) of Gene_expression (Levels) of NF-L in frontal cortex associated with urological neuroanatomy
1) Confidence 0.43 Published 1997 Journal Neuroreport Section Abstract Doc Link 9189892 Disease Relevance 0.20 Pain Relevance 0.59
Compared with the control, the levels of NF-L, NF-M, NF-H, beta-actin, tau, MAP2 proteins decreased and the level of alpha-tubulin increased in high ACR group, the levels of alpha-tubulin, beta-tubulin and MAP2 increased in low ACR group.
Negative_regulation (decreased) of Gene_expression (levels) of NF-L
2) Confidence 0.27 Published 2006 Journal Neurochem. Res. Section Abstract Doc Link 16845587 Disease Relevance 0.25 Pain Relevance 0.07

General Comments

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